S, R, S)-AHPC-PEG2-Tos is a combination von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with a tosyl group. The tosyl group is a good leaving group for nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is useful for synthesis of PROTAC compounds and molecules for targeted protein degradation.
MedKoo Cat#: 122178
Name: (S, R, S)-AHPC-PEG2-Tos
CAS#: N/A
Chemical Formula: C34H44N4O8S2
Exact Mass: 700.2601
Molecular Weight: 700.87
Elemental Analysis: C, 58.27; H, 6.33; N, 7.99; O, 18.26; S, 9.15
The following data is based on the product molecular weight 700.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
