Propargyl-PEG4-S-PEG4-acid is a PEG linker containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages.
MedKoo Cat#: 122027
Name: Propargyl-PEG4-S-PEG4-acid
CAS#: 2055041-20-6
Chemical Formula: C22H40O10S
Exact Mass: 496.2342
Molecular Weight: 496.61
Elemental Analysis: C, 53.21; H, 8.12; O, 32.22; S, 6.46
The following data is based on the product molecular weight 496.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
