MedKoo Cat#: 121161 | Name: 3-Mercaptopropionic acid NHS ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

3-Mercaptopropionic acid NHS ester is a ProTAC building block. NHS ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protein-polymer conjugates and the synthesis of protein-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use a crosslinking agent, this material can also be used to install functional groups post-polymerization.

Chemical Structure

3-Mercaptopropionic acid NHS ester
3-Mercaptopropionic acid NHS ester
CAS#117235-10-6

Theoretical Analysis

MedKoo Cat#: 121161

Name: 3-Mercaptopropionic acid NHS ester

CAS#: 117235-10-6

Chemical Formula: C7H9NO4S

Exact Mass: 203.0252

Molecular Weight: 203.21

Elemental Analysis: C, 41.37; H, 4.46; N, 6.89; O, 31.49; S, 15.78

Price and Availability

Size Price Availability Quantity
500mg USD 350.00 2 Weeks
1g USD 550.00 2 Weeks
2g USD 950.00 2 Weeks
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Synonym
3-Mercaptopropionic acid NHS ester; 3 Mercaptopropionic acid NHS ester; 3Mercaptopropionic acid NHS ester
IUPAC/Chemical Name
3-Mercaptopropanyl-N-hydroxysuccinimide ester
InChi Key
UTBOEPMMEANMPS-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2
SMILES Code
SCCC(ON1C(CCC1=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 203.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
An S, Fu L. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. doi: 10.1016/j.ebiom.2018.09.005. Epub 2018 Sep 14. PMID: 30224312; PMCID: PMC6197674.