Synonym
PM 1000, 10-Methyl-11-hydroxyaporphine, 11-Hmapp, 11-Hydroxy-10-methylaporphine
IUPAC/Chemical Name
4H-Dibenzo(de,g)quinolin-11-ol, 5,6,6a,7-tetrahydro-6,10-dimethyl-, (R)-
InChi Key
YGOZTDLAUVOPMF-OAHLLOKOSA-N
InChi Code
InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1
SMILES Code
OC1=C2C3=C4C(CCN(C)[C@]4([H])CC2=CC=C1C)=CC=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
265.36
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Trisomboon H, Malaivijitnond S, Watanabe G, Cherdshewasart W, Taya K. The estrogenic effect of Pueraria mirifica on gonadotrophin levels in aged monkeys. Endocrine. 2006 Feb;29(1):129-34. doi: 10.1385/ENDO:29:1:129. PMID: 16622301.
2: Kariper IA, Üstündağ Z, Caglayan MO. A sensitive spectrophotometric ellipsometry based Aptasensor for the vascular endothelial growth factor detection. Talanta. 2021 Apr 1;225:121982. doi: 10.1016/j.talanta.2020.121982. Epub 2020 Dec 9. PMID: 33592730.
3: Disha, Kumari P, Nayak MK, Kumar P. An electrochemical biosensing platform for progesterone hormone detection using magnetic graphene oxide. J Mater Chem B. 2021 Jul 7;9(26):5264-5271. doi: 10.1039/d1tb00380a. PMID: 34151922.
4: Alex A V, Deosarkar T, N C, Mukherjee A. An ultra-sensitive and selective AChE based colorimetric detection of malathion using silver nanoparticle- graphene oxide (Ag-GO) nanocomposite. Anal Chim Acta. 2021 Jan 15;1142:73-83. doi: 10.1016/j.aca.2020.10.057. Epub 2020 Nov 2. PMID: 33280706.
5: Manonai J, Seif C, Böhler G, Jünemann KP. The effect of Pueraria mirifica on cytologic and urodynamic findings in ovariectomized rats. Menopause. 2009 Mar- Apr;16(2):350-6. doi: 10.1097/gme.0b013e318188b279. PMID: 19098688.
6: Roumeliotis TS, Van Heyst BJ. Size fractionated particulate matter emissions from a broiler house in Southern Ontario, Canada. Sci Total Environ. 2007 Sep 20;383(1-3):174-82. doi: 10.1016/j.scitotenv.2007.05.003. Epub 2007 Jun 19. PMID: 17582466.
7: Trisomboon H, Malaivijitnond S, Watanabe G, Taya K. Ovulation block by Pueraria mirifica: a study of its endocrinological effect in female monkeys. Endocrine. 2005 Feb;26(1):33-9. doi: 10.1385/ENDO:26:1:033. PMID: 15805583.
8: Russell LD, Peterson RN, Russell TA, Hunt W. Electrophoretic map of boar sperm plasma membrane polypeptides and localization and fractionation of specific polypeptide subclasses. Biol Reprod. 1983 Mar;28(2):393-413. doi: 10.1095/biolreprod28.2.393. PMID: 6188498.
9: Sun F, Yin Z, Lun X, Zhao Y, Li R, Shi F, Yu X. Deposition velocity of PM2.5 in the winter and spring above deciduous and coniferous forests in Beijing, China. PLoS One. 2014 May 19;9(5):e97723. doi: 10.1371/journal.pone.0097723. PMID: 24842850; PMCID: PMC4026521.
10: Egli M, Lybrand TP. Enhanced Dispersion and Polarization Interactions Achieved through Dithiophosphate Group Incorporation Yield a Dramatic Binding Affinity Increase for an RNA Aptamer-Thrombin Complex. J Am Chem Soc. 2019 Mar 13;141(10):4445-4452. doi: 10.1021/jacs.9b00104. Epub 2019 Mar 5. PMID: 30794399.
