FBA inhibitor 2a11 | CAS#2605897-57-0 | Resistant

MedKoo Cat#: 208261 | Name: FBA inhibitor 2a11

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FBA inhibitor 2a11 has potent inhibitory activity against resistant fungi, establishing a structural foundation and providing a promising strategy for the design of potent antifungal drugs.

Chemical Structure

FBA inhibitor 2a11

CAS#2605897-57-0

Theoretical Analysis

MedKoo Cat#: 208261

Name: FBA inhibitor 2a11

CAS#: 2605897-57-0

Chemical Formula: C15H13NOSe

Exact Mass: 303.0162

Molecular Weight: 302.24

Elemental Analysis: Chemical Formula: C15H13NOSe Exact Mass: 303.0162 Molecular Weight: 302.2350 Elemental Analysis: C, 59.61; H, 4.34; N, 4.63; O, 5.29; Se, 26.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

FBA-inhibitor 2a11, FBA inhibitor-2a11, FBA-inhibitor-2a11

IUPAC/Chemical Name

2-(4-Ethylphenyl)-1,2-benzoselenazol-3-one

InChi Key

MCSRHGLYNCIRNI-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H13NOSe/c1-2-11-7-9-12(10-8-11)16-15(17)13-5-3-4-6-14(13)18-16/h3-10H,2H2,1H3

SMILES Code

O=C1N(C2=CC=C(CC)C=C2)[Se]C3=CC=CC=C13

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 302.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Wen W, Cao H, Huang Y, Tu J, Wan C, Wan J, Han X, Chen H, Liu J, Rao L, Su C, Peng C, Sheng C, Ren Y. Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis. J Med Chem. 2022 Feb 10;65(3):2656-2674. doi: 10.1021/acs.jmedchem.1c02102. Epub 2022 Jan 31. PMID: 35099959.