CUN43389, also known as SMS1-IN-1 and SAPA1j, is a SAPA inhibitor (sphingomyelin synthase 1 inhibitor). SAPA 1j was found to be the most potent SMS1 inhibitor with an IC50 value of 2.1 μM in in vitro assay. This compound was first reported n Bioorg Med Chem 2015 Sep 15;23(18):6173-84. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 556086
Name: CUN43389
CAS#: 1807943-38-9
Chemical Formula: C23H23BrN2O4
Exact Mass: 502.0562
Molecular Weight: 503.41
Elemental Analysis: C, 54.88; H, 4.61; Br, 15.87; N, 5.56; O, 12.71; S, 6.37
The following data is based on the product molecular weight 503.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
