N-Nitroso-N-methylaniline | CAS#614-00-6 | Tumor inducer

MedKoo Cat#: 112025 | Name: N-Nitroso-N-methylaniline

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

N-Nitroso-N-methylaniline is an N-nitrosamine. It induces the formation of esophageal, pharyngeal, and tongue tumors in rats when administered at a concentration of 200 mg/L in the drinking water or 15 mg/ml via oral gavage. N-Nitroso-N-methylaniline is toxic to rats with LD50 values of 336 and 225 mg/kg for male and female rats, respectively. It reduces survival of hamsters but only induces a low incidence of tumors in this species when administered at a dose of 5 mg/week for a total dose of 1.8 mmol.

Chemical Structure

N-Nitroso-N-methylaniline

CAS#614-00-6

Theoretical Analysis

MedKoo Cat#: 112025

Name: N-Nitroso-N-methylaniline

CAS#: 614-00-6

Chemical Formula: C7H8N2O

Exact Mass: 136.0637

Molecular Weight: 136.15

Elemental Analysis: C, 61.75; H, 5.92; N, 20.58; O, 11.75

Price and Availability

Size	Price	Availability
25mg	USD 280.00	2 Weeks
50mg	USD 540.00	2 Weeks
100mg	USD 840.00	2 Weeks
250mg	USD 1,340.00	2 Weeks

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Related CAS #

No Data

Synonym

N methyl N Nitrosoaniline; NMA; NSC 137; NSC-137; NSC137

IUPAC/Chemical Name

N-methyl-N-phenylnitrous amide

InChi Key

MAXCWSIJKVASQC-UHFFFAOYSA-N

InChi Code

InChI=1S/C7H8N2O/c1-9(8-10)7-5-3-2-4-6-7/h2-6H,1H3

SMILES Code

O=NN(C1=CC=CC=C1)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 136.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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