MedKoo Cat#: 578323 | Name: NQ-304

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NQ-304 is a biochemical that has been shown to suppress the PI3K/Akt and ERK1/2 signaling pathways to inhibit VSMC proliferation.

Chemical Structure

NQ-304
NQ-304
CAS#153973-24-1

Theoretical Analysis

MedKoo Cat#: 578323

Name: NQ-304

CAS#: 153973-24-1

Chemical Formula:

Exact Mass:

Molecular Weight:

Elemental Analysis:

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NQ-304; NQ 304; NQ304
IUPAC/Chemical Name
2-chloro-3-(4-hexylphenyl)-amino-1,4-naphthoquinone
InChi Key
KTYQIPWUZFJVJY-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H22ClNO2/c1-2-3-4-5-8-15-11-13-16(14-12-15)24-20-19(23)21(25)17-9-6-7-10-18(17)22(20)26/h6-7,9-14,24H,2-5,8H2,1H3
SMILES Code
CCCCCCc1ccc(NC2=C(Cl)C(=O)c3ccccc3C2=O)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Kim TJ, Yun YP. Antiproliferative activity of NQ304, a synthetic 1,4-naphthoquinone, is mediated via the suppressions of the PI3K/Akt and ERK1/2 signaling pathways in PDGF-BB-stimulated vascular smooth muscle cells. Vascul Pharmacol. 2007 Jan;46(1):43-51. doi: 10.1016/j.vph.2006.06.007. Epub 2006 Jun 16. PMID: 16875883.