MedKoo Cat#: 578127 | Name: Nialamide monohydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nialamide monohydrochloride is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant. It was withdrawn by Pfizer several decades ago due to the risk of hepatotoxicity.

Chemical Structure

Nialamide monohydrochloride
CAS#1161-03-1

Theoretical Analysis

MedKoo Cat#: 578127

Name: Nialamide monohydrochloride

CAS#: 1161-03-1

Chemical Formula: C16H19ClN4O2

Exact Mass: 334.1197

Molecular Weight: 334.80

Elemental Analysis: C, 57.40; H, 5.72; Cl, 10.59; N, 16.73; O, 9.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Nialamide monohydrochloride; Nialamide hydrochloride, Nialamide HCl
IUPAC/Chemical Name
Isonicotinic acid, 2-(2-(benzylcarbamoyl)ethyl)hydrazide, hydrochloride
InChi Key
XPLZAZCGEUUFJL-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H18N4O2.ClH/c21-15(18-12-13-4-2-1-3-5-13)8-11-19-20-16(22)14-6-9-17-10-7-14;/h1-7,9-10,19H,8,11-12H2,(H,18,21)(H,20,22);1H
SMILES Code
[Cl-].O=C(CCNNC(=O)c1ccncc1)[NH2+]Cc2ccccc2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 334.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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