MedKoo Cat#: 578209 | Name: NITR-5

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NITR-5 is a photosensitive calcium chelator.

Chemical Structure

NITR-5
CAS#109232-36-2

Theoretical Analysis

MedKoo Cat#: 578209

Name: NITR-5

CAS#: 109232-36-2

Chemical Formula: C31H31N3O15

Exact Mass: 685.1755

Molecular Weight: 685.59

Elemental Analysis: C, 54.31; H, 4.56; N, 6.13; O, 35.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NITR-5; NITR 5; NITR5
IUPAC/Chemical Name
Glycine, N-(2-(2-(2-(bis(carboxymethyl)amino)-5-(hydroxy(6-nitro-1,3-benzodioxol-5-yl)methyl)phenoxy)ethoxy)-4-methylphenyl)-N-(carboxymethyl)-
InChi Key
SQBFKIHOMAMLEJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H31N3O15/c1-17-2-4-20(32(12-27(35)36)13-28(37)38)23(8-17)46-6-7-47-24-9-18(3-5-21(24)33(14-29(39)40)15-30(41)42)31(43)19-10-25-26(49-16-48-25)11-22(19)34(44)45/h2-5,8-11,31,43H,6-7,12-16H2,1H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)
SMILES Code
Cc1ccc(N(CC(=O)O)CC(=O)O)c(OCCOc2cc(ccc2N(CC(=O)O)CC(=O)O)C(O)c3cc4OCOc4cc3[N+](=O)[O-])c1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 685.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Lea TJ, Fenton MJ, Potter JD, Ashley CC. Rapid activation by photolysis of nitr-5 in skinned fibres of the striated adductor muscle from the scallop. Biochim Biophys Acta. 1990 May 16;1034(2):186-94. doi: 10.1016/0304-4165(90)90075-8. PMID: 2112954. 2. Simnett SJ, Lipscomb S, Ashley CC, Potter JD, Mulligan IP. The thiadiazinone EMD 57033 speeds the activation of skinned cardiac muscle produced by the photolysis of nitr-5. Pflugers Arch. 1994 Jul;427(5-6):550-2. doi: 10.1007/BF00374274. PMID: 7971154. 3. Patel JR, Coronado R, Moss RL. Cardiac sarcoplasmic reticulum phosphorylation increases Ca2+ release induced by flash photolysis of nitr-5. Circ Res. 1995 Nov;77(5):943-9. doi: 10.1161/01.res.77.5.943. PMID: 7554148.