MedKoo Cat#: 578036 | Name: ND-7001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ND-7001 is a PDE2 inhibitor.

Chemical Structure

ND-7001
ND-7001
CAS#855170-53-5

Theoretical Analysis

MedKoo Cat#: 578036

Name: ND-7001

CAS#: 855170-53-5

Chemical Formula: C24H21N3O3

Exact Mass: 399.1583

Molecular Weight: 399.45

Elemental Analysis: C, 72.17; H, 5.30; N, 10.52; O, 12.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ND-7001; ND 7001; ND7001
IUPAC/Chemical Name
3-(2,3-Dihydro-8-methoxy-1-methyl-2-oxo-7-phenyl-1H-1,4-benzodiazepin-5-yl)benzamide
InChi Key
WYTGWTBNDXWMMB-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H21N3O3/c1-27-20-13-21(30-2)18(15-7-4-3-5-8-15)12-19(20)23(26-14-22(27)28)16-9-6-10-17(11-16)24(25)29/h3-13H,14H2,1-2H3,(H2,25,29)
SMILES Code
COc1cc2N(C)C(=O)CN=C(c3cccc(c3)C(=O)N)c2cc1c4ccccc4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 399.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Lueptow LM, Zhan CG, O'Donnell JM. Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice. Psychopharmacology (Berl). 2016 Feb;233(3):447-56. doi: 10.1007/s00213-015-4129-1. Epub 2015 Nov 2. PMID: 26525565. 2. Masood A, Huang Y, Hajjhussein H, Xiao L, Li H, Wang W, Hamza A, Zhan CG, O'Donnell JM. Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling. J Pharmacol Exp Ther. 2009 Nov;331(2):690-9. doi: 10.1124/jpet.109.156729. Epub 2009 Aug 14. PMID: 19684253; PMCID: PMC2775258. 3. Heine C, Sygnecka K, Scherf N, Berndt A, Egerland U, Hage T, Franke H. Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures. Neurosignals. 2013;21(3-4):197-212. doi: 10.1159/000338020. Epub 2012 Aug 31. PMID: 22947663.