Synonym
Mannose phosphate sodium; α-D-Mannopyranosyl phosphate;
IUPAC/Chemical Name
sodium (3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methyl hydrogen phosphate
InChi Key
ZALKNDISPIVVKC-UHFFFAOYSA-M
InChi Code
InChI=1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1
SMILES Code
OC(O1)C(O)C(O)C(O)C1COP([O-])(O)=O.[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
282.12
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Enotarpi J, Tontini M, Balocchi C, van der Es D, Auberger L, Balducci E, Carboni F, Proietti D, Casini D, Filippov DV, Overkleeft HS, van der Marel GA, Colombo C, Romano MR, Berti F, Costantino P, Codeé JDC, Lay L, Adamo R. A stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A. Nat Commun. 2020 Sep 7;11(1):4434. doi: 10.1038/s41467-020-18279-x. Erratum in: Nat Commun. 2020 Nov 25;11(1):6155. PMID: 32895393; PMCID: PMC7477203.
2: Lamosa P, Lourenço EC, d'Avó F, Nobre A, Bandeiras TM, da Costa MS, Ventura MR, Santos H. A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus. Extremophiles. 2015 Mar;19(2):373-82. doi: 10.1007/s00792-014-0723-0. Epub 2015 Jan 3. PMID: 25555708.
3: Gao Q, Tontini M, Brogioni G, Nilo A, Filippini S, Harfouche C, Polito L, Romano MR, Costantino P, Berti F, Adamo R, Lay L. Immunoactivity of protein conjugates of carba analogues from Neisseria meningitidis a capsular polysaccharide. ACS Chem Biol. 2013 Nov 15;8(11):2561-7. doi: 10.1021/cb400463u. Epub 2013 Sep 19. PMID: 24000773.
4: Gao Q, Zaccaria C, Tontini M, Poletti L, Costantino P, Lay L. Synthesis and preliminary biological evaluation of carba analogues from Neisseria meningitidis A capsular polysaccharide. Org Biomol Chem. 2012 Sep 7;10(33):6673-81. doi: 10.1039/c2ob25222h. PMID: 22850927.
