YycG inhibitor 62 | CAS#unknown | YycG inhibitor

MedKoo Cat#: 466022 | Name: YycG inhibitor 62

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YycG inhibitor 62 is a novel YycG inhibitor, significantly inhibited biofilm formation in static and dynamic conditions.

Chemical Structure

YycG inhibitor 62

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 466022

Name: YycG inhibitor 62

CAS#: unknown

Chemical Formula: C30H22ClN3O6S2

Exact Mass: 619.0639

Molecular Weight: 620.09

Elemental Analysis: C, 58.11; H, 3.58; Cl, 5.72; N, 6.78; O, 15.48; S, 10.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

YycG inhibitor 62; Yyc G inhibitor 62; Yyc-G inhibitor 62;

IUPAC/Chemical Name

4-(benzofuran-2-carbonyl)-1-(5-((2-chloro-4-methylbenzyl)thio)-1,3,4-thiadiazol-2-yl)-3-hydroxy-5-(4-hydroxy-3-methoxyphenyl)-1,5-dihydro-2H-pyrrol-2-one

InChi Key

BIYNDOBOXIBFAA-UHFFFAOYSA-N

InChi Code

InChI=1S/C30H22ClN3O6S2/c1-15-7-8-18(19(31)11-15)14-41-30-33-32-29(42-30)34-25(17-9-10-20(35)22(13-17)39-2)24(27(37)28(34)38)26(36)23-12-16-5-3-4-6-21(16)40-23/h3-13,25,35,37H,14H2,1-2H3

SMILES Code

O=C1N(C2=NN=C(SCC3=CC=C(C)C=C3Cl)S2)C(C4=CC=C(O)C(OC)=C4)C(C(C5=CC6=CC=CC=C6O5)=O)=C1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 620.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Chen Z, Song K, Shang Y, Xiong Y, Lyu Z, Chen J, Zheng J, Li P, Wu Y, Gu C, Xie Y, Deng Q, Yu Z, Zhang J, Qu D. Selection and Identification of Novel Antibacterial Agents against Planktonic Growth and Biofilm Formation of Enterococcus faecalis. J Med Chem. 2021 Oct 28;64(20):15037-15052. doi: 10.1021/acs.jmedchem.1c00939. Epub 2021 Oct 16. PMID: 34657423. 2: Huang RZ, Zheng LK, Liu HY, Pan B, Hu J, Zhu T, Wang W, Jiang DB, Wu Y, Wu YC, Han SQ, Qu D. Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis. Acta Pharmacol Sin. 2012 Mar;33(3):418-25. doi: 10.1038/aps.2011.166. Epub 2012 Jan 9. Erratum in: Acta Pharmacol Sin. 2013 Nov;34(11):1484. PMID: 22231397; PMCID: PMC4077129.