Claficapavir | CAS# 2055732-24-4 | Antiviral

MedKoo Cat#: 577736 | Name: Claficapavir

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Claficapavir is a specific nucleocapsid protein (NC) inhibitor that strongly binds the HIV-1 NC. By inhibiting the chaperone properties of NC, Claficapavir exhibits antiviral activity against HIV-1.

Chemical Structure

Claficapavir

CAS#2055732-24-4

Theoretical Analysis

MedKoo Cat#: 577736

Name: Claficapavir

CAS#: 2055732-24-4

Chemical Formula: C17H12ClNO4S2

Exact Mass: 392.9896

Molecular Weight: 393.86

Elemental Analysis: C, 51.84; H, 3.07; Cl, 9.00; N, 3.56; O, 16.25; S, 16.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

A1752; A 1752; A-1752; Claficapavir

IUPAC/Chemical Name

3-[(5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid

InChi Key

YZLFZFALAZYTCI-ZROIWOOFSA-N

InChi Code

InChI=1S/C17H12ClNO4S2/c18-11-3-1-10(2-4-11)13-6-5-12(23-13)9-14-16(22)19(17(24)25-14)8-7-15(20)21/h1-6,9H,7-8H2,(H,20,21)/b14-9-

SMILES Code

O=C(O)CCN(C/1=O)C(SC1=C/C2=CC=C(C3=CC=C(Cl)C=C3)O2)=S

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 393.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Kim MJ, Kim SH, Park JA, Yu KL, Jang SI, Kim BS, Lee ES, You JC. Identification and characterization of a new type of inhibitor against the human immunodeficiency virus type-1 nucleocapsid protein. Retrovirology. 2015 Nov 6;12:90. doi: 10.1186/s12977-015-0218-9. PMID: 26545586; PMCID: PMC4636002.