EPZ-719 is a novel and potent SETD2 inhibitor ( IC50 = 0.005 μM) with a high selectivity over other histone methyltransferases. SET domain-containing protein 2 (SETD2), a histone methyltransferase, has been identified as a target of interest in certain hematological malignancies, including multiple myeloma.
MedKoo Cat#: 465853
Name: EPZ-719 mesylate
CAS#: EPZ-719 mesylate
Chemical Formula: C23H35FN4O6S2
Exact Mass: 0.0000
Molecular Weight: 546.67
Elemental Analysis: C, 50.53; H, 6.45; F, 3.48; N, 10.25; O, 17.56; S, 11.73
The following data is based on the product molecular weight 546.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
