RMC-4630 is a SHP2 inhibitor. RMC-4630 shows reasonable tolerability and preliminary signs of clinical activity in patients with NSCLC harboring KRAS mutations.
MedKoo Cat#: 465808
Name: RMC-4630
CAS#: 2172652-48-9
Chemical Formula: C20H27ClN6O2S
Exact Mass: 450.1605
Molecular Weight: 450.99
Elemental Analysis: C, 53.27; H, 6.03; Cl, 7.86; N, 18.64; O, 7.10; S, 7.11
The following data is based on the product molecular weight 450.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |