Benzylphthalimide | CAS#2142-01-0 | androgen antagonist

MedKoo Cat#: 591791 | Name: Benzylphthalimide

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Benzylphthalimide is a potent non-steroidal androgen antagonists.

Chemical Structure

Benzylphthalimide

CAS#2142-01-0

Theoretical Analysis

MedKoo Cat#: 591791

Name: Benzylphthalimide

CAS#: 2142-01-0

Chemical Formula: C15H11NO2

Exact Mass: 237.0790

Molecular Weight: 237.26

Elemental Analysis: C, 75.94; H, 4.67; N, 5.90; O, 13.49

Price and Availability

Size	Price	Availability	Quantity
5g	USD 250.00	2 Weeks
25g	USD 450.00	2 weeks

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Related CAS #

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Synonym

Benzylphthalimide; NSC 2771; NSC-2771; NSC2771; N-Benzylphthalimide

IUPAC/Chemical Name

1H-Isoindole-1,3(2H)-dione, 2-(phenylmethyl)-

InChi Key

WITXFYCLPDFRNM-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H11NO2/c17-14-12-8-4-5-9-13(12)15(18)16(14)10-11-6-2-1-3-7-11/h1-9H,10H2

SMILES Code

O=C1N(CC2=CC=CC=C2)C(C3=C1C=CC=C3)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 237.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dabral S, Turberg M, Wanninger A, Bolm C, Hernández JG. Mechanochemical Lignin-Mediated Strecker Reaction. Molecules. 2017 Jan 17;22(1). pii: E146. doi: 10.3390/molecules22010146. PubMed PMID: 28106742. 2: Cheong MY, Ariffin A, Khan MN. Kinetic coupled with UV spectral evidence for near-irreversible nonionic micellar binding of N-benzylphthalimide under the typical reaction conditions: an observation against a major assumption of the pseudophase micellar model. J Phys Chem B. 2007 Oct 25;111(42):12185-94. Epub 2007 Oct 3. PubMed PMID: 17914797. 3: Hashimoto Y. Novel biological response modifiers derived from thalidomide. Curr Med Chem. 1998 Jun;5(3):163-78. Review. PubMed PMID: 9562600. 4: Sasaki K, Shibata Y, Hashimoto Y, Iwasaki S. Benzylphthalimides and phenethylphthalimides with thalidomide-like activity on the production of tumor necrosis factor alpha. Biol Pharm Bull. 1995 Sep;18(9):1228-33. PubMed PMID: 8845811. 5: Shibata Y, Sasaki K, Nishimura K, Hashimoto Y, Iwasaki S. Enhancement of phorbol ester-induced production of tumor necrosis factor-alpha by 2,6-dimethylphenylphthalimide. Biol Pharm Bull. 1994 Nov;17(11):1532-4. PubMed PMID: 7703981.