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MedKoo Cat#: 161007 | Name: NEMERTELLINE

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NEMERTELLINE potentially possesses neurotoxic, anti-feeding, and anti-fouling activities. NEMERTELLINE is a quaterpyridine neurotoxin that has been isolated from a Hoplonemertine sea worm. NEMERTELLINE shows a structural resemblance to the tobacco constituent nicotelline.

Chemical Structure

NEMERTELLINE
NEMERTELLINE
CAS#59697-14-2

Theoretical Analysis

MedKoo Cat#: 161007

Name: NEMERTELLINE

CAS#: 59697-14-2

Chemical Formula: C20H14N4

Exact Mass: 310.1200

Molecular Weight: 310.36

Elemental Analysis: C, 77.40; H, 4.55; N, 18.05

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NEMERTELLINE;
IUPAC/Chemical Name
3,2':3',4'':2'',3'''-quaterpyridine
InChi Key
SWWRILUGNLIYGG-UHFFFAOYSA-N
InChi Code
1S/C20H14N4/c1-4-16(13-21-8-1)19-12-15(7-11-23-19)18-6-3-10-24-20(18)17-5-2-9-22-14-17/h1-14H
SMILES Code
C1=CC(=CN=C1)C2=CC(=CC=N2)C3=C(N=CC=C3)C4=CN=CC=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 310.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bouillon A, Voisin AS, Robic A, Lancelot JC, Collot V, Rault S. An efficient two-step total synthesis of the quaterpyridine nemertelline. J Org Chem. 2003 Dec 26;68(26):10178-80. doi: 10.1021/jo034805b. PMID: 14682721. 2: Kem WR, Soti F, Rocca JR, Johnson JV. New Pyridyl and Dihydroisoquinoline Alkaloids Isolated from the Chevron Nemertean Amphiporus angulatus. Mar Drugs. 2024 Mar 22;22(4):141. doi: 10.3390/md22040141. PMID: 38667758; PMCID: PMC11050936. 3: Kem WR, Scott KN, Duncan JH. Hoplonemertine worms -- a new source of pyridine neurotoxins. Experientia. 1976 Jun 15;32(6):684-6. doi: 10.1007/BF01919831. PMID: 181266. 4: Kem WR, Soti F, Rittschof D. Inhibition of barnacle larval settlement and crustacean toxicity of some hoplonemertine pyridyl alkaloids. Biomol Eng. 2003 Jul;20(4-6):355-61. doi: 10.1016/s1389-0344(03)00049-2. PMID: 12919820.