MedKoo Cat#: 471054 | Name: EPPTB
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

EPPTB is a selective antagonist of the trace amine-associated receptor 1 (TAAR1).

Chemical Structure

EPPTB
EPPTB
CAS#1110781-88-8

Theoretical Analysis

MedKoo Cat#: 471054

Name: EPPTB

CAS#: 1110781-88-8

Chemical Formula: C20H21F3N2O2

Exact Mass: 378.1555

Molecular Weight: 378.40

Elemental Analysis: C, 63.48; H, 5.59; F, 15.06; N, 7.40; O, 8.46

Price and Availability

Size Price Availability Quantity
50mg USD 350.00 2 Weeks
100mg USD 550.00 2 Weeks
200mg USD 850.00 2 Weeks
500mg USD 1,650.00 2 Weeks
1g USD 2,750.00 2 Weeks
2g USD 4,650.00 2 Weeks
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Related CAS #
Synonym
Ro 5212773; Ro5212773; Ro-5212773; EPPTB;
IUPAC/Chemical Name
N-(3-ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)-benzamide
InChi Key
KLFVWQCQUXXLOU-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H21F3N2O2/c1-2-27-16-7-5-6-15(13-16)24-19(26)14-8-9-18(25-10-3-4-11-25)17(12-14)20(21,22)23/h5-9,12-13H,2-4,10-11H2,1H3,(H,24,26)
SMILES Code
O=C(NC1=CC=CC(OCC)=C1)C2=CC=C(N3CCCC3)C(C(F)(F)F)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 378.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. H. Stalder et al. Selective antagonists of mouse trace amine-associated receptor 1 (mTAAR1): discovery of EPPTB (RO5212773). Bioorg Med Chem Lett. 2011 Feb 15;21(4):1227-31. 2. A. Bradaia et al. The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):20081-6.