Synonym
Sanipirol-4-d7; 4-Aminosalicylic Acid-d7; p-Aminosalicylic Acid-d7; 4-ASA-d7; PAS-d7
IUPAC/Chemical Name
4-(amino-d2)-2-(hydroxy-d)benzoic-d3 acid-d
InChi Key
WUBBRNOQWQTFEX-PNENHCSXSA-N
InChi Code
InChI=1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)/i1D,2D,3D/hD4
SMILES Code
O=C(C1=C([2H])C([2H])=C(C([2H])=C1O[2H])N([2H])[2H])O[2H]
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
160.18
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Youmans, G.P., Raleigh, G.W., and Youmans, A.S. The tuberculostatic action of para-aminosalicylic acid. J. Bacteriol. 54(4), 409-416 (1947).
2. Chakraborty, S., Gruber, T., Barry, C.E., III, et al. Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis. Science 339(6115), 88-91 (2013).
3. Peng, D., Li, J., Deng, Y., et al. Sodium para-aminosalicylic acid inhibits manganese-induced NLRP3 inflammasome-dependent pyroptosis by inhibiting NF-κB pathway activation and oxidative stress. J. Neuroinflammation 17(1), 343 (2020).
4. Terai, T., Ito, H., Kikuchi, K., et al. Salicylic-acid derivatives as antennae for ratiometric luminescent probes based on lanthanide complexes. Chemistry 18(24), 7377-7381 (2012).
