MedKoo Cat#: 465564 | Name: UUN-14238
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UUN-14238 is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers. UUN-14238 is part of a range of functionalized tool molecules for PROTAC® Degrader R&D. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).

Chemical Structure

UUN-14238
UUN-14238
CAS#2222114-23-8

Theoretical Analysis

MedKoo Cat#: 465564

Name: UUN-14238

CAS#: 2222114-23-8

Chemical Formula: C17H18ClFN4O4

Exact Mass: 396.1001

Molecular Weight: 396.80

Elemental Analysis: C, 51.46; H, 4.57; Cl, 8.93; F, 4.79; N, 14.12; O, 16.13

Price and Availability

Size Price Availability Quantity
25mg USD 380.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
UUN-14238; UUN14238; UUN 14238; Pomalidomide 5'-fluoro-6'-piperazine;
IUPAC/Chemical Name
2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride
InChi Key
UQDWELYJNPCIGK-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H17FN4O4.ClH/c18-11-7-9-10(8-13(11)21-5-3-19-4-6-21)17(26)22(16(9)25)12-1-2-14(23)20-15(12)24;/h7-8,12,19H,1-6H2,(H,20,23,24);1H
SMILES Code
FC1=C(C=C2C(N(C3CCC(NC3=O)=O)C(C2=C1)=O)=O)N4CCNCC4.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 396.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL