MedKoo Cat#: 577364 | Name: Methdilazine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methdilazine is a first-generation antihistamine with anticholinergic properties of the phenothiazine class.

Chemical Structure

Methdilazine
Methdilazine
CAS#1982-37-2

Theoretical Analysis

MedKoo Cat#: 577364

Name: Methdilazine

CAS#: 1982-37-2

Chemical Formula: C18H20N2S

Exact Mass: 296.1347

Molecular Weight: 296.43

Elemental Analysis: C, 72.93; H, 6.80; N, 9.45; S, 10.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Methdilazine; Tacaryl
IUPAC/Chemical Name
Phenothiazine, 10-((1-methyl-3-pyrrolidinyl)methyl)-
InChi Key
HTMIBDQKFHUPSX-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H20N2S/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20/h2-9,14H,10-13H2,1H3
SMILES Code
CN1CCC(CN2c3ccccc3Sc4ccccc24)C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Toxicity Data: Guinea Pig - LD50, Oral (263mg/kg) | Effects: None reported. Human - TDLo, Oral (4mg/kg) | Effects: Gastrointestinal Changes; Somnolence & General Depressed Activity; Dyspnea Mouse - LD50, Intraperitoneal (183mg/kg) | Effects: None reported. Mouse - LD50, Oral (225mg/kg) | Effects: None reported. Rat - LD50, Oral (162mg/kg) | Effects: None reported. Source: "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 29, 1972. "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 379, 1969. Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. Physical Properties: Melting Point: 87-88 deg C logP (octanol-water): 5.23 Water Solubility: 0.348 mg/L Vapor Pressure: 1.73E-07 mm Hg

Preparing Stock Solutions

The following data is based on the product molecular weight 296.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL