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MedKoo Cat#: 577300 | Name: Methiothepin methanesulfonate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methiothepin methanesulfonate is an inhibitor of HCV infection and cell-to-cell transmission that acts by targeting the HCV E2 glycoprotein.

Chemical Structure

Methiothepin methanesulfonate
Methiothepin methanesulfonate
CAS#51482-89-4

Theoretical Analysis

MedKoo Cat#: 577300

Name: Methiothepin methanesulfonate

CAS#: 51482-89-4

Chemical Formula: C21H28N2O3S3

Exact Mass: 452.1262

Molecular Weight: 452.65

Elemental Analysis: C, 55.72; H, 6.24; N, 6.19; O, 10.60; S, 21.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Methiothepin methanesulfonate
IUPAC/Chemical Name
Piperazine, 1-(10,11-dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methyl-, methanesulfonate
InChi Key
CZMDZGZYKOGLJY-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H24N2S2.CH4O3S/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20;1-5(2,3)4/h3-8,14,18H,9-13H2,1-2H3;1H3,(H,2,3,4)
SMILES Code
CN1CCN(C2CC3=CC=CC=C3SC4=CC=C(SC)C=C24)CC1.CS(=O)(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 452.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Miyazato M, Kaiho Y, Kamo I, Chancellor MB, Sugaya K, de Groat WC, Yoshimura N. Effect of duloxetine, a norepinephrine and serotonin reuptake inhibitor, on sneeze-induced urethral continence reflex in rats. Am J Physiol Renal Physiol. 2008 Jul;295(1):F264-71. doi: 10.1152/ajprenal.90241.2008. Epub 2008 May 14. PubMed PMID: 18480175; PubMed Central PMCID: PMC2494509. 2: Hudecki MS, Pollina CM, Bhargava AK, Hudecki RS. Screening of antiserotoninergic drugs with the genetically dystrophic chicken. Arch Neurol. 1980 Sep;37(9):545-50. PubMed PMID: 6448038. 3: Masala A, Devilla L, Delitala G, Alagna S, Rovasio PP, Capitanio GL. Action of the serotoninergic and dopaminergic antagonist methiothepin maleate on serum prolactin and growth hormone levels in man. Panminerva Med. 1979 Apr-Jun;21(2):65-8. PubMed PMID: 554040.