MedKoo Cat#: 146365 | Name: Solketal

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Solketal is a chemical compound formed by the reaction of glycerol and acetone, classified as a ketal. It is commonly used as a solvent, fuel additive, and intermediate in the synthesis of pharmaceuticals and fine chemicals. In biofuel applications, Solketal improves fuel stability and reduces particulate emissions by enhancing combustion efficiency. Its mechanism involves acting as an oxygenate, introducing additional oxygen into the fuel mixture, which promotes cleaner and more complete combustion.

Chemical Structure

Solketal
Solketal
CAS#100-79-8

Theoretical Analysis

MedKoo Cat#: 146365

Name: Solketal

CAS#: 100-79-8

Chemical Formula: C6H12O3

Exact Mass: 132.0786

Molecular Weight: 132.16

Elemental Analysis: C, 54.53; H, 9.15; O, 36.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Solketal;
IUPAC/Chemical Name
(2,2-dimethyl-1,3-dioxolan-4-yl)methanol
InChi Key
RNVYQYLELCKWAN-UHFFFAOYSA-N
InChi Code
1S/C6H12O3/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3
SMILES Code
CC1(C)OCC(CO)O1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 132.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dias CN, Viana AM, Cunha-Silva L, Balula SS. The Role of the Heterogeneous Catalyst to Produce Solketal from Biodiesel Waste: The Key to Achieve Efficiency. Nanomaterials (Basel). 2024 May 9;14(10):828. doi: 10.3390/nano14100828. PMID: 38786785; PMCID: PMC11124048. 2: Dias CN, Santos-Vieira ICMS, Gomes CR, Mirante F, Balula SS. Heteropolyacids@Silica Heterogeneous Catalysts to Produce Solketal from Glycerol Acetalization. Nanomaterials (Basel). 2024 Apr 23;14(9):733. doi: 10.3390/nano14090733. PMID: 38727327; PMCID: PMC11085283. 3: Julião D, Mirante F, Balula SS. Easy and Fast Production of Solketal from Glycerol Acetalization via Heteropolyacids. Molecules. 2022 Oct 4;27(19):6573. doi: 10.3390/molecules27196573. PMID: 36235109; PMCID: PMC9572551. 4: Prete P, Trano S, Zaccagnini P, Fagiolari L, Amici J, Lamberti A, Proto A, Bella F, Cucciniello R. Glycerol Carbonate and Solketal Carbonate as Circular Economy Bricks for Supercapacitors and Potassium Batteries. ChemSusChem. 2024 Dec 20;17(24):e202401636. doi: 10.1002/cssc.202401636. Epub 2024 Oct 18. PMID: 39150696; PMCID: PMC11660737. 5: Gujar JP, Modhera B. Green synthesis of solketal from glycerol using metal- modified ZSM-5 zeolite catalysts: process optimization. Environ Sci Pollut Res Int. 2024 Apr;31(19):28353-28367. doi: 10.1007/s11356-024-33031-4. Epub 2024 Mar 27. PMID: 38538995. 6: Kowalska-Kuś J, Malaika A, Held A, Jankowska A, Janiszewska E, Zieliński M, Nowińska K, Kowalak S, Końska K, Wróblewski K. Synthesis of Solketal Catalyzed by Acid-Modified Pyrolytic Carbon Black from Waste Tires. Molecules. 2024 Aug 29;29(17):4102. doi: 10.3390/molecules29174102. PMID: 39274951; PMCID: PMC11397316. 7: Saleem S, Rangou S, Abetz C, Filiz V, Abetz V. Isoporous Membranes from Novel Polystyrene-b-poly(4-vinylpyridine)-b-poly(solketal methacrylate) (PS-b-P4VP-b-PSMA) Triblock Terpolymers and Their Post- Modification. Polymers (Basel). 2019 Dec 26;12(1):41. doi: 10.3390/polym12010041. PMID: 31888039; PMCID: PMC7023574. 8: Santamaría L, Korili SA, Gil A. Solketal Removal from Aqueous Solutions Using Activated Carbon and a Metal-Organic Framework as Adsorbents. Materials (Basel). 2021 Nov 13;14(22):6852. doi: 10.3390/ma14226852. PMID: 34832254; PMCID: PMC8623111. 9: Perosa A, Moraschini A, Selva M, Noè M. Synthesis of the Fatty Esters of Solketal and Glycerol-Formal: Biobased Specialty Chemicals. Molecules. 2016 Jan 30;21(2):170. doi: 10.3390/molecules21020170. PMID: 26840287; PMCID: PMC6273257. 10: Rambhia DA, Veluturla S, Narula A. Parametric and kinetic study of solvent- free synthesis of solketal using ion exchange resin. Turk J Chem. 2022 Feb 23;46(3):881-889. doi: 10.55730/1300-0527.3376. PMID: 37720614; PMCID: PMC10503983. 11: Lin CY, Tsai SM. Emission characteristics of a diesel engine fueled with nanoemulsions of continuous diesel dispersed with solketal droplets. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2020;55(3):224-229. doi: 10.1080/10934529.2019.1682366. Epub 2019 Nov 1. PMID: 31674258. 12: Sadjadi S, Tarighi S, Delangiz M, Heravi M. Heteropolyacid supported on ionic liquid decorated hierarchical faujasite zeolite as an efficient catalyst for glycerol acetalization to solketal. Sci Rep. 2023 Sep 21;13(1):15703. doi: 10.1038/s41598-023-42956-8. PMID: 37735246; PMCID: PMC10514292. 13: Lin CY, Tsai SM. Comparison of Engine Performance between Nano- and Microemulsions of Solketal Droplets Dispersed in Diesel Assisted by Microwave Irradiation. Molecules. 2019 Sep 26;24(19):3497. doi: 10.3390/molecules24193497. PMID: 31561537; PMCID: PMC6804196. 14: Huang X, Zhang G, Zhang L, Zhang Q. Continuous Flow Synthesis of a ZSM-5 Film in Capillary Microchannel for Efficient Production of Solketal. ACS Omega. 2020 Aug 14;5(33):20784-20791. doi: 10.1021/acsomega.0c01573. PMID: 32875212; PMCID: PMC7450500. 15: Türck J, Schmitt F, Anthofer L, Türck R, Ruck W, Krahl J. Extension of Biodiesel Aging Mechanism-the Role and Influence of Methyl Oleate and the Contribution of Alcohols Through the Use of Solketal. ChemSusChem. 2023 Sep 8;16(17):e202300263. doi: 10.1002/cssc.202300263. Epub 2023 Jul 10. PMID: 37220243. 16: Ao S, Gouda SP, Saikia L, Gurunathan B, Rokhum SL. Biochar carbon nanodots for catalytic acetalization of biodiesel by-product crude glycerol to solketal: process optimization by RSM and life cycle cost analysis. Sci Rep. 2024 Aug 29;14(1):20140. doi: 10.1038/s41598-024-69553-7. PMID: 39209866; PMCID: PMC11362544. 17: Huang Y, Zhang G, Zhang Q. Preparation of the WO X /MCM-41 Solid Acid Catalyst and the Catalytic Performance for Solketal Synthesis. ACS Omega. 2021 Jan 30;6(5):3875-3883. doi: 10.1021/acsomega.0c05671. PMID: 33585766; PMCID: PMC7876846. 18: Rocha KSC, Queiroz MSR, Gomes BS, Dallago R, de Souza ROMA, Guimarães DO, Itabaiana I Jr, Leal ICR. Lipases of Endophytic Fungi Stemphylium lycopersici and Sordaria sp.: Application in the synthesis of solketal derived Monoacylglycerols. Enzyme Microb Technol. 2020 Dec;142:109664. doi: 10.1016/j.enzmictec.2020.109664. Epub 2020 Sep 6. PMID: 33220859. 19: Janiszewska E, Kowalska-Kuś J, Wiktorowska J, Jankowska A, Tabero A, Held A, Kowalak S. Generation of Acid Sites in Nanostructured KIT-6 Using Different Methods to Obtain Efficient Acidic Catalysts for Glycerol Acetalization to Solketal. Molecules. 2024 Nov 21;29(23):5512. doi: 10.3390/molecules29235512. PMID: 39683672; PMCID: PMC11643615. 20: Maurya S, Chandra Sharma Y. A facile approach for the synthesis of solketal, a fuel additive, from biowaste glycerol using transition metal-based solid acid catalysts. RSC Adv. 2024 Dec 16;14(53):39511-39522. doi: 10.1039/d4ra05455e. PMID: 39687335; PMCID: PMC11647200.