MedKoo Cat#: 414692 | Name: Oxophoebine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oxophoebine has been identified as a DNA topoisomerase inhibitor

Chemical Structure

Oxophoebine
Oxophoebine
CAS#109175-37-3

Theoretical Analysis

MedKoo Cat#: 414692

Name: Oxophoebine

CAS#: 109175-37-3

Chemical Formula: C20H15NO6

Exact Mass: 365.0899

Molecular Weight: 365.34

Elemental Analysis: C, 65.75; H, 4.14; N, 3.83; O, 26.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Oxophoebine
IUPAC/Chemical Name
7H-Benzo(de)(1,3)benzodioxolo(5,6-g)quinolin-7-one, 1,2,3-trimethoxy-
InChi Key
JHBLLXUDHWJZMA-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H15NO6/c1-23-18-9-4-5-21-16-14(9)15(19(24-2)20(18)25-3)10-6-12-13(27-8-26-12)7-11(10)17(16)22/h4-7H,8H2,1-3H3
SMILES Code
O=C1C(C(C2=C(OC)C(OC)=C(OC)C3=CC=NC1=C32)=C4)=CC5=C4OCO5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 365.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rayanil KO, Prempree C, Nimgirawath S. The first total syntheses of (±)-norphoebine, dehydrophoebine, oxophoebine, dehydrocrebanine, oxocrebanine and uthongine and their cytotoxicity against three human cancer cell lines. J Asian Nat Prod Res. 2016 Nov;18(11):1042-56. doi: 10.1080/10286020.2016.1177025. Epub 2016 May 5. PMID: 27146697. 2: Harrigan GG, Gunatilaka AA, Kingston DG, Chan GW, Johnson RK. Isolation of bioactive and other oxoaporphine alkaloids from two annonaceous plants, Xylopia aethiopica and Miliusa cf. banacea. J Nat Prod. 1994 Jan;57(1):68-73. doi: 10.1021/np50103a009. PMID: 8158166. 3: Dholvitayakhun A, Trachoo N, Sakee U, Cushnie TP. Potential applications for Annona squamosa leaf extract in the treatment and prevention of foodborne bacterial disease. Nat Prod Commun. 2013 Mar;8(3):385-8. PMID: 23678817.