Prohexadione | CAS#88805-35-0 | Plant growth regulator

MedKoo Cat#: 465310 | Name: Prohexadione

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Prohexadione is a plant growth regulator. It inhibits the gibberellin plant hormone biosynthesis enzyme 3β-hydroxylase when used at concentrations of 0.1, 1, and 10 mM. It reduces the shoot length of peanut plants when applied at 0.5, 1.5, and 4.5 kg/hectare. Prohexadione also inhibits jumonji domain-containing 2A (JMJD2A) demethylase when used at a concentration of 1 mM and induces the differentiation of mouse neurospheres into neurons at 1, 1.5, and 2 mM. Formulations containing prohexadione have been used as plant growth regulators in agriculture.

Chemical Structure

Prohexadione

CAS#88805-35-0

Theoretical Analysis

MedKoo Cat#: 465310

Name: Prohexadione

CAS#: 88805-35-0

Chemical Formula: C10H12O5

Exact Mass: 212.0685

Molecular Weight: 212.20

Elemental Analysis: C, 56.60; H, 5.70; O, 37.70

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 550.00	2 Weeks
10mg	USD 950.00	2 Weeks

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Related CAS #

No Data

Synonym

Prohexadione; BX-112; BX 112; BX112;

IUPAC/Chemical Name

3,5-dioxo-4-propionylcyclohexane-1-carboxylic acid

InChi Key

BUCOQPHDYUOJSI-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H12O5/c1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13/h5,9H,2-4H2,1H3,(H,14,15)

SMILES Code

O=C(O)C1CC(C(C(CC)=O)C(C1)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

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Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 212.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Homma M, Uchida K, Wakabayashi T, Mizutani M, Takikawa H, Sugimoto Y. 2-oxoglutarate-dependent dioxygenases and BAHD acyltransferases drive the structural diversification of orobanchol in Fabaceae plants. Front Plant Sci. 2024 Apr 18;15:1392212. doi: 10.3389/fpls.2024.1392212. PMID: 38699535; PMCID: PMC11063326. 2: Deng P, Khan A, Zhou H, Lu X, Zhao H, Du Y, Wang Y, Feng N, Zheng D. Application of prohexadione-calcium priming affects Brassica napus L. seedlings by regulating morph-physiological characteristics under salt stress. PeerJ. 2024 Apr 26;12:e17312. doi: 10.7717/peerj.17312. PMID: 38685942; PMCID: PMC11057430. 3: Li D, Yang J, Dai Z, Chen Y, Shao Z, Wang C, Jin X, Wang Y, Feng L. Prohexadione-calcium improves grape quality by regulating endogenous hormones, sugar and acid metabolism and related enzyme activities in grape berries. BMC Plant Biol. 2024 Feb 19;24(1):122. doi: 10.1186/s12870-024-04803-4. PMID: 38373883; PMCID: PMC10875774. 4: Zuo G, Huo J, Yang X, Mei W, Zhang R, Khan A, Feng N, Zheng D. Photosynthetic mechanisms underlying NaCl-induced salinity tolerance in rice (Oryza sativa). BMC Plant Biol. 2024 Jan 10;24(1):41. doi: 10.1186/s12870-024-04723-3. PMID: 38195408; PMCID: PMC10777521. 5: Yuan X, Gdanetz K, Outwater CA, Slack SM, Sundin GW. Evaluation of Plant Defense Inducers and Plant Growth Regulators for Fire Blight Management Using Transcriptome Studies and Field Assessments. Phytopathology. 2023 Dec;113(12):2152-2164. doi: 10.1094/PHYTO-04-23-0147-KC. Epub 2023 Dec 23. PMID: 37399041. 6: Li Y, Zhou H, Feng N, Zheng D, Ma G, Feng S, Liu M, Yu M, Huang X, Huang A. Physiological and transcriptome analysis reveals that prohexadione-calcium promotes rice seedling's development under salt stress by regulating antioxidant processes and photosynthesis. PLoS One. 2023 Jun 14;18(6):e0286505. doi: 10.1371/journal.pone.0286505. PMID: 37315011; PMCID: PMC10266641. 7: Ye H, Luo Y, Li Y, Wang X, He H, Jiang J, Yu J, Zhang C. Residues and Dietary Risk Assessment of Prohexadione-Ca and Uniconazole in Oryza sativa L. and Citrus reticulata Blanco by Liquid Chromatography-Tandem Mass Spectrometry. Molecules. 2023 Mar 13;28(6):2611. doi: 10.3390/molecules28062611. PMID: 36985589; PMCID: PMC10059882. 8: Zhang R, Zheng D, Feng N, Qiu QS, Zhou H, Meng F, Huang X, Huang A, Li Y. Prohexadione-calcium alleviates the leaf and root damage caused by salt stress in rice (Oryza sativa L.) at the tillering stage. PLoS One. 2023 Mar 17;18(3):e0279192. doi: 10.1371/journal.pone.0279192. PMID: 36930609; PMCID: PMC10022774. 9: Zhang R, Zheng D, Feng N, Qiu QS, Zhou H, Liu M, Li Y, Meng F, Huang X, Huang A, Li Y. Prohexadione calcium enhances rice growth and tillering under NaCl stress. PeerJ. 2023 Feb 6;11:e14804. doi: 10.7717/peerj.14804. PMID: 36778152; PMCID: PMC9910188. 10: Huang X, Zheng D, Feng N, Huang A, Zhang R, Meng F, Jie Y, Mu B, Mu D, Zhou H. Effects of prohexadione calcium spraying during the booting stage on panicle traits, yield, and related physiological characteristics of rice under salt stress. PeerJ. 2023 Jan 23;11:e14673. doi: 10.7717/peerj.14673. PMID: 36710858; PMCID: PMC9879151. 11: Liang F, Xu W, Wu H, Zheng B, Liang Q, Li Y, Wang S. Widely targeted metabolite profiling of mango stem apex during floral induction by compond of mepiquat chloride, prohexadione-calcium and uniconazole. PeerJ. 2022 Dec 12;10:e14458. doi: 10.7717/peerj.14458. PMID: 36530389; PMCID: PMC9753738. 12: Sabir IA, Manzoor MA, Shah IH, Abbas F, Liu X, Fiaz S, Shah AN, Jiu S, Wang J, Abdullah M, Zhang C. Evolutionary and Integrative Analysis of Gibberellin- Dioxygenase Gene Family and Their Expression Profile in Three Rosaceae Genomes (F. vesca, P. mume, and P. avium) Under Phytohormone Stress. Front Plant Sci. 2022 Jul 7;13:942969. doi: 10.3389/fpls.2022.942969. PMID: 35874024; PMCID: PMC9302438. 13: Mhetre VB, Patel VB, Singh SK, Mishra GP, Verma MK, Kumar C, Dahuja A, Kumar S, Singh R, Wasim Siddiqui M. Unraveling the pathways influencing the berry color and firmness of grapevine cv. Flame Seedless treated with bioregulators using biochemical and RNA-Seq analysis under semi-arid subtropics. Food Chem (Oxf). 2022 Jun 25;5:100116. doi: 10.1016/j.fochms.2022.100116. PMID: 35818381; PMCID: PMC9270244. 14: Berli FJ, Alonso R, Pharis RP, Bottini R. Applied GA5 , GA4 , and GA4/7 increase berry number per bunch, yield, and grape quality for winemaking in Vitis vinifera L. cv. Malbec. J Sci Food Agric. 2022 May;102(7):2950-2959. doi: 10.1002/jsfa.11635. Epub 2021 Nov 26. PMID: 34767265. 15: Sun H, Cui H, Zhang J, Kang J, Wang Z, Li M, Yi F, Yang Q, Long R. Gibberellins Inhibit Flavonoid Biosynthesis and Promote Nitrogen Metabolism in Medicago truncatula. Int J Mol Sci. 2021 Aug 27;22(17):9291. doi: 10.3390/ijms22179291. PMID: 34502200; PMCID: PMC8431309. 16: Aćimović SG, Meredith CL, Santander RD, Khodadadi F. Proof of Concept for Shoot Blight and Fire Blight Canker Management with Postinfection Spray Applications of Prohexadione-Calcium and Acibenzolar-S-Methyl in Apple. Plant Dis. 2021 Dec;105(12):4095-4105. doi: 10.1094/PDIS-08-20-1744-RE. Epub 2021 Dec 3. PMID: 34232052. 17: Feng N, Yu M, Li Y, Jin D, Zheng D. Prohexadione-calcium alleviates saline- alkali stress in soybean seedlings by improving the photosynthesis and up- regulating antioxidant defense. Ecotoxicol Environ Saf. 2021 Sep 1;220:112369. doi: 10.1016/j.ecoenv.2021.112369. Epub 2021 Jun 2. PMID: 34090109. 18: Carra B, Pasa MS, Abreu ES, Dini M, Pasa CP, Ciotta MN, Herter FG, Mello- Farias P. Plant growth regulators to increase fruit set and yield of 'Rocha' pear trees in Southern Brazil. An Acad Bras Cienc. 2021 Feb 1;93(3):e20180680. doi: 10.1590/0001-3765202120180860. PMID: 33533799. 19: Lerner F, Pfenning M, Picard L, Lerchl J, Hollenbach E. Prohexadione calcium is herbicidal to the sunflower root parasite Orobanche cumana. Pest Manag Sci. 2021 Apr;77(4):1893-1902. doi: 10.1002/ps.6216. Epub 2020 Dec 21. PMID: 33284472. 20: Laužikė K, Sirgedaitė-Šėžienė V, Uselis N, Samuolienė G. The Impact of Stress Caused By Light Penetration and Agrotechnological Tools on Photosynthetic Behavior of Apple Trees. Sci Rep. 2020 Jun 8;10(1):9177. doi: 10.1038/s41598-020-66179-3. PMID: 32514086; PMCID: PMC7280272.