Laminin (925-933) | CAS#110590-60-8

MedKoo Cat#: 462791 | Name: Laminin (925-933)

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Laminin (925-933) is a peptide fragment corresponding to the laminin β1 chain.1 It binds to the laminin receptor when used at a concentration of 1 mg/ml. Laminin (925-933) stimulates the attachment of HT-1080 and CHO cells to culture plates when used at concentrations of 100 and 300 µg/ml. It induces chemotaxis of, as well as inhibits chemotaxis induced by full-length laminin, but not fibronectin, in B16/F10 murine melanoma cells. Laminin (925-933) conjugated to an agarose hydrogel backbone enhances neurite outgrowth in isolated chick embryo dorsal root ganglia and PC12 cells.

Chemical Structure

Laminin (925-933)

CAS#110590-60-8

Theoretical Analysis

MedKoo Cat#: 462791

Name: Laminin (925-933)

CAS#: 110590-60-8

Chemical Formula: C40H62N12O14S

Exact Mass: 966.4229

Molecular Weight: 967.07

Elemental Analysis: C, 49.68; H, 6.46; N, 17.38; O, 23.16; S, 3.32

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 550.00	2 Weeks
10mg	USD 950.00	2 Weeks

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Related CAS #

No Data

Synonym

CDPGYIGSR;

IUPAC/Chemical Name

L-cysteinyl-L-aspartyl-L-prolylglycyl-L-tyrosyl-L-isoleucylglycyl-L-serylarginine

InChi Key

NGBBIWFVAWMQKZ-RMYNKKRNSA-N

InChi Code

InChI=1S/C40H62N12O14S/c1-3-20(2)32(37(63)46-17-30(56)48-27(18-53)35(61)49-24(39(65)66)6-4-12-44-40(42)43)51-34(60)25(14-21-8-10-22(54)11-9-21)47-29(55)16-45-36(62)28-7-5-13-52(28)38(64)26(15-31(57)58)50-33(59)23(41)19-67/h8-11,20,23-28,32,53-54,67H,3-7,12-19,41H2,1-2H3,(H,45,62)(H,46,63)(H,47,55)(H,48,56)(H,49,61)(H,50,59)(H,51,60)(H,57,58)(H,65,66)(H4,42,43,44)/t20-,23-,24?,25-,26-,27-,28-,32-/m0/s1

SMILES Code

O=C(NCC(N[C@H](C(N[C@@H]([C@H](CC)C)C(NCC(N[C@H](C(NC(C(O)=O)CCCNC(N)=N)=O)CO)=O)=O)=O)CC1=CC=C(C=C1)O)=O)[C@H]2N(CCC2)C([C@@H](NC([C@H](CS)N)=O)CC(O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Laminin (925-933) is a peptide derived from residues 925-933 of the Laminin B1 chain that binds to the laminin receptor.

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMF	30.0	31.02
	DMSO	30.0	31.02
	PBS (pH 7.2)	10.0	10.34

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 967.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.