NSC 1969 | CAS#879-37-8 | Tryptophan metabolite

MedKoo Cat#: 465298 | Name: NSC 1969

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSC 1969 is an endogenous metabolite of tryptophan and intermediate in the biosynthesis of the major plant, fungal, and bacterial auxin hormone, indole-3-acetic acid (IAA), in phytopathogenic bacteria. It is formed directly from tryptophan in plants by tryptophan monooxygenase or, indirectly, through indole-3-acetonitrile or indole-3-acetaldoxime intermediates. Exogenous application of NSC 1969 (20 µM) increases the expression of ami1, the gene encoding amidase 1, the enzyme that catalyzes the synthesis of indole-3-acetic acid from NSC 1969, in Arabidopsis. It reduces relative primary root elongation in Arabidopsis mutants that have increased amidase activity and lower indole-3-acetamide levels, but not in wild-type Arabidopsis, when used at concentrations of 1 and 10 µM. NSC 1969 inhibits mouse and rat liver, as well as P. fluorescens and tryptophan 2,3-dioxygenase but not rabbit intestine or mouse epididymis indoleamine 2,3-dioxygenase.

Chemical Structure

NSC 1969

CAS#879-37-8

Theoretical Analysis

MedKoo Cat#: 465298

Name: NSC 1969

CAS#: 879-37-8

Chemical Formula: C10H10N2O

Exact Mass: 174.0793

Molecular Weight: 174.20

Elemental Analysis: C, 68.95; H, 5.79; N, 16.08; O, 9.18

Price and Availability

Size	Price	Availability
10g	USD 210.00	2 Weeks
25g	USD 350.00	2 Weeks
50g	USD 560.00	2 Weeks
100g	USD 860.00	2 Weeks

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Related CAS #

No Data

Synonym

NSC 1969; NSC1969; NSC-1969; Indole-3-acetamide; IAM;

IUPAC/Chemical Name

2-(1H-indol-3-yl)acetamide

InChi Key

ZOAMBXDOGPRZLP-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H10N2O/c11-10(13)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5H2,(H2,11,13)

SMILES Code

O=C(N)CC1=CNC2=C1C=CC=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	DMF	30.0	172.21
	DMSO	30.0	172.21
	DMSO:PBS (pH 7.2) (1:9)	0.1	0.57

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 174.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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