SB 24011 | inhibitor of STING-TRIM29 interaction | CAS#1497415-41-4

MedKoo Cat#: 127995 | Name: SB 24011

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SB 24011 is an inhibitor of STING-TRIM29 interaction (IC50 = 3.85 μM in vitro). SB 24011 binds to STING and inhibits TRIM29-E3 ligase interaction to increase cellular STING levels.

Chemical Structure

SB 24011

CAS#1497415-41-4

Theoretical Analysis

MedKoo Cat#: 127995

Name: SB 24011

CAS#: 1497415-41-4

Chemical Formula: C34H38N4O7

Exact Mass: 614.2740

Molecular Weight: 614.70

Elemental Analysis: C, 66.43; H, 6.23; N, 9.11; O, 18.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

SB 24011; SB-24011; SB24011

IUPAC/Chemical Name

4-((R)-4-(4-hydroxybenzyl)-2-isopropyl-5-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-1(2H)-yl)-3-nitro-N-(((S)-tetrahydrofuran-2-yl)methyl)benzamide

InChi Key

UZVHJOMTRTYDKL-BHDXBOSCSA-N

InChi Code

InChI=1S/C34H38N4O7/c1-22(2)32-34(41)36(20-24-6-11-27(39)12-7-24)26(17-23-8-13-28(44-3)14-9-23)21-37(32)30-15-10-25(18-31(30)38(42)43)33(40)35-19-29-5-4-16-45-29/h6-15,18,21-22,29,32,39H,4-5,16-17,19-20H2,1-3H3,(H,35,40)/t29-,32+/m0/s1

SMILES Code

CC([C@H]1N(C2=C(C=C(C=C2)C(NC[C@@H]3CCCO3)=O)[N+]([O-])=O)C=C(N(C1=O)CC4=CC=C(C=C4)O)CC5=CC=C(C=C5)OC)C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 614.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.