MedKoo Cat#: 341380 | Name: Isocaproaldehyde
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Isocaproaldehyde is a biochemical.

Chemical Structure

Isocaproaldehyde
Isocaproaldehyde
CAS#1119-16-0

Theoretical Analysis

MedKoo Cat#: 341380

Name: Isocaproaldehyde

CAS#: 1119-16-0

Chemical Formula: C6H12O

Exact Mass: 100.0888

Molecular Weight: 100.16

Elemental Analysis: C, 71.95; H, 12.08; O, 15.97

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 Weeks
250mg USD 650.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Isocaproaldehyde; Isohexanal.
IUPAC/Chemical Name
4-Methylvaleraldehyde
InChi Key
JGEGJYXHCFUMJF-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H12O/c1-6(2)4-3-5-7/h5-6H,3-4H2,1-2H3
SMILES Code
CC(C)CCC=O
Appearance
Liquid
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 100.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kankolongo Cibaka ML, Decourrière L, Lorenzo-Alonso CJ, Bodart E, Robiette R, Collin S. 3-Sulfanyl-4-methylpentan-1-ol in Dry-Hopped Beers: First Evidence of Glutathione S-Conjugates in Hop (Humulus lupulus L.). J Agric Food Chem. 2016 Nov 16;64(45):8572-8582. Epub 2016 Nov 7. PubMed PMID: 27933902. 2: Yoshimoto FK, Jung IJ, Goyal S, Gonzalez E, Guengerich FP. Isotope-Labeling Studies Support the Electrophilic Compound I Iron Active Species, FeO(3+), for the Carbon-Carbon Bond Cleavage Reaction of the Cholesterol Side-Chain Cleavage Enzyme, Cytochrome P450 11A1. J Am Chem Soc. 2016 Sep 21;138(37):12124-41. doi: 10.1021/jacs.6b04437. Epub 2016 Sep 12. PubMed PMID: 27571509; PubMed Central PMCID: PMC5289895. 3: Pastel E, Pointud JC, Martinez A, Lefrançois-Martinez AM. Aldo-Keto Reductases 1B in Adrenal Cortex Physiology. Front Endocrinol (Lausanne). 2016 Jul 22;7:97. doi: 10.3389/fendo.2016.00097. eCollection 2016. Review. PubMed PMID: 27499746; PubMed Central PMCID: PMC4956669. 4: Inagaki H, Kiyokawa Y, Tamogami S, Watanabe H, Takeuchi Y, Mori Y. Identification of a pheromone that increases anxiety in rats. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18751-6. doi: 10.1073/pnas.1414710112. Epub 2014 Dec 15. PubMed PMID: 25512532; PubMed Central PMCID: PMC4284601. 5: Endo S, Matsunaga T, Fujita A, Tajima K, El-Kabbani O, Hara A. Rat aldose reductase-like protein (AKR1B14) efficiently reduces the lipid peroxidation product 4-oxo-2-nonenal. Biol Pharm Bull. 2010;33(11):1886-90. Erratum in: Biol Pharm Bull. 2011;34(6):937. PubMed PMID: 21048316. 6: Chung R, Endo S, Hara A, El-Kabbani O. Crystallization and preliminary X-ray analysis of a rat aldose reductase-like protein (AKR1B14). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Apr 1;65(Pt 4):395-7. doi: 10.1107/S1744309109009762. Epub 2009 Mar 25. PubMed PMID: 19342790; PubMed Central PMCID: PMC2664770. 7: Baumann C, Davies B, Peters M, Kaufmann-Reiche U, Lessl M, Theuring F. AKR1B7 (mouse vas deferens protein) is dispensable for mouse development and reproductive success. Reproduction. 2007 Jul;134(1):97-109. PubMed PMID: 17641092. 8: Kotokorpi P, Gardmo C, Nyström CS, Mode A. Activation of the glucocorticoid receptor or liver X receptors interferes with growth hormone-induced akr1b7 gene expression in rat hepatocytes. Endocrinology. 2004 Dec;145(12):5704-13. Epub 2004 Sep 9. PubMed PMID: 15358674. 9: Lefrançois-Martinez AM, Bertherat J, Val P, Tournaire C, Gallo-Payet N, Hyndman D, Veyssière G, Bertagna X, Jean C, Martinez A. Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors. J Clin Endocrinol Metab. 2004 Jun;89(6):3010-9. PubMed PMID: 15181092. 10: Val P, Aigueperse C, Ragazzon B, Veyssière G, Lefrançois-Martinez AM, Martinez A. Adrenocorticotropin/3',5'-cyclic AMP-mediated transcription of the scavenger akr1-b7 gene in adrenocortical cells is dependent on three functionally distinct steroidogenic factor-1-responsive elements. Endocrinology. 2004 Feb;145(2):508-18. Epub 2003 Nov 6. PubMed PMID: 14605009. 11: Baron S, Manin M, Aigueperse C, Berger M, Jean C, Veyssière G, Morel L. Hormonal and developmental regulation of the mouse aldose reductase-like gene akr1b7 expression in Leydig cells. J Mol Endocrinol. 2003 Aug;31(1):71-81. PubMed PMID: 12914526. 12: Martinez A, Val P, Sahut-Barnola I, Aigueperse C, Veyssière G, Lefrançois-Martinez AM. Steroidogenic factor-1 controls the aldose reductase akr1b7 gene promoter in transgenic mice through an atypical binding site. Endocrinology. 2003 May;144(5):2111-20. PubMed PMID: 12697720. 13: Val P, Aigueperse C, Lefrançois-Martinez AM, Jean C, Veyssière G, Martinez A. Role of three SF-1 binding sites in the expression of the mvdp/akr1-b7 isocaproaldehyde reductase in Y1 cells. Endocr Res. 2002 Nov;28(4):527-33. Review. PubMed PMID: 12530658. 14: Martinez A, Aigueperse C, Val P, Dussault M, Tournaire C, Berger M, Veyssière G, Jean C, Lefrançois Martinez A. Physiological functions and hormonal regulation of mouse vas deferens protein (AKR1B7) in steroidogenic tissues. Chem Biol Interact. 2001 Jan 30;130-132(1-3):903-17. PubMed PMID: 11306105. 15: Sahut-Barnola I, Lefrancois-Martinez AM, Jean C, Veyssiere G, Martinez A. Adrenal tumorigenesis targeted by the corticotropin-regulated promoter of the aldo-keto reductase AKR1B7 gene in transgenic mice. Endocr Res. 2000 Nov;26(4):885-98. PubMed PMID: 11196467. 16: Aigueperse C, Val P, Pacot C, Darne C, Lalli E, Sassone-Corsi P, Veyssiere G, Jean C, Martinez A. SF-1 (steroidogenic factor-1), C/EBPbeta (CCAAT/enhancer binding protein), and ubiquitous transcription factors NF1 (nuclear factor 1) and Sp1 (selective promoter factor 1) are required for regulation of the mouse aldose reductase-like gene (AKR1B7) expression in adrenocortical cells. Mol Endocrinol. 2001 Jan;15(1):93-111. PubMed PMID: 11145742. 17: Lefrançois-Martinez AM, Tournaire C, Martinez A, Berger M, Daoudal S, Tritsch D, Veyssière G, Jean C. Product of side-chain cleavage of cholesterol, isocaproaldehyde, is an endogenous specific substrate of mouse vas deferens protein, an aldose reductase-like protein in adrenocortical cells. J Biol Chem. 1999 Nov 12;274(46):32875-80. PubMed PMID: 10551851. 18: Matsuura K, Deyashiki Y, Bunai Y, Ohya I, Hara A. Aldose reductase is a major reductase for isocaproaldehyde, a product of side-chain cleavage of cholesterol, in human and animal adrenal glands. Arch Biochem Biophys. 1996 Apr 15;328(2):265-71. PubMed PMID: 8645003. 19: Otsuka H, Floss HG. Steric course of the rhodium-catalyzed decarbonylation of chiral 4-methyl-[1-3H,2-2H1]pentanal. Z Naturforsch C. 1987 Apr;42(4):449-54. PubMed PMID: 2955591. 20: Rabe T, Rabe D, Bierwirth AM, Runnebaum B. New assays for the enzymatic conversion of cholesterol to pregnenolone. Steroids. 1981 May;37(5):555-71. PubMed PMID: 6894812.