Synonym
MVL5; MVL 5; MVL-5;
IUPAC/Chemical Name
N-(2-(2-((3-aminopropyl)amino)-5-(bis(3-aminopropyl)amino)pentanamido)ethyl)-3,4-bis(((Z)-octadec-9-en-1-yl)oxy)benzamide
InChi Key
DBQMYYNZVOQICL-CLFAGFIQSA-N
InChi Code
InChI=1S/C59H111N7O4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-51-69-56-41-40-54(53-57(56)70-52-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)58(67)64-46-47-65-59(68)55(63-45-36-42-60)39-35-48-66(49-37-43-61)50-38-44-62/h17-20,40-41,53,55,63H,3-16,21-39,42-52,60-62H2,1-2H3,(H,64,67)(H,65,68)/b19-17-,20-18-
SMILES Code
O=C(NCCNC(C(CCCN(CCCN)CCCN)NCCCN)=O)C1=CC(OCCCCCCCC/C=C\CCCCCCCC)=C(OCCCCCCCC/C=C\CCCCCCCC)C=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
982.58
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Chan CL, Ewert KK, Majzoub RN, Hwu YK, Liang KS, Leal C, Safinya CR. Optimizing cationic and neutral lipids for efficient gene delivery at high serum content. J Gene Med. 2014 Mar-Apr;16(3-4):84-96. doi: 10.1002/jgm.2762. PMID: 24753287; PMCID: PMC4051313.
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5: Bouxsein NF, McAllister CS, Ewert KK, Samuel CE, Safinya CR. Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA. Biochemistry. 2007 Apr 24;46(16):4785-92. doi: 10.1021/bi062138l. Epub 2007 Mar 29. PMID: 17391006.
