ICI-190622 HCl | CAS# 103586-13-6 | Biochemical

MedKoo Cat#: 576493 | Name: ICI-190622 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI-190622 HCl is an anticonvulsant and anxiolytic.

Chemical Structure

ICI-190622 HCl

CAS#103586-13-6

Theoretical Analysis

MedKoo Cat#: 576493

Name: ICI-190622 HCl

CAS#: 103586-13-6

Chemical Formula: C15H18ClN5O

Exact Mass: 319.1200

Molecular Weight: 319.79

Elemental Analysis: C, 56.34; H, 5.67; Cl, 11.09; N, 21.90; O, 5.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ICI-190622 hydrochloride; ICI-190622 HCl; ICI190622 HCl; ICI 190622 HCl

IUPAC/Chemical Name

1H-Pyrazolo(3,4-b)pyridine-5-carboxamide, 4-amino-1-(3-pentynyl)-N-2-propenyl-, monohydrochloride

InChi Key

TUEMLOZMUNWHLM-UHFFFAOYSA-N

InChi Code

1S/C15H17N5O.ClH/c1-3-5-6-8-20-14-11(10-19-20)13(16)12(9-18-14)15(21)17-7-4-2;/h4,9-10H,2,6-8H2,1H3,(H2,16,18)(H,17,21);1H

SMILES Code

Cl.CC#CCCn1ncc2c(N)c(cnc12)C(=O)NCC=C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 319.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Patel JB, Meiners BA, Salama AI, Malick JB, U'Prichard DC, Giles RE, Goldberg ME, Bare TM. Preclinical studies with pyrazolopyridine non-benzodiazepine anxiolytics: ICI 190,622. Pharmacol Biochem Behav. 1988 Apr;29(4):775-9. doi: 10.1016/0091-3057(88)90205-5. PMID: 2901116. 2. Bare TM, McLaren CD, Campbell JB, Firor JW, Resch JF, Walters CP, Salama AI, Meiners BA, Patel JB. Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents. J Med Chem. 1989 Dec;32(12):2561-73. doi: 10.1021/jm00132a011. PMID: 2573731.