MedKoo Cat#: 465232 | Name: DMRIE

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DMRIE is a cationic lipid for RNA and vaccine delivery. DMRIE is an important component for making DMRIE-C Transfection Reagent. DMRIE-C can also be used for in vivo delivery of DNA. DMRIE-C is a 1:1 (M/M) liposome formulation of the cationic lipid DMRIE (1,2-dimyristyloxy-propyl-3-dimethyl-hydroxy ethyl ammonium bromide) and cholesterol in membrane-filtered water.

Chemical Structure

DMRIE
DMRIE
CAS#153312-64-2 (bromide)

Theoretical Analysis

MedKoo Cat#: 465232

Name: DMRIE

CAS#: 153312-64-2 (bromide)

Chemical Formula: C35H74BrNO3

Exact Mass: 635.4852

Molecular Weight: 636.89

Elemental Analysis: C, 66.01; H, 11.71; Br, 12.55; N, 2.20; O, 7.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
153312-64-2 (bromide) 191980-81-1 (cation)
Synonym
DMRIE; dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium;
IUPAC/Chemical Name
N-(2-hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)propan-1-aminium bromide
InChi Key
WALUVDCNGPQPOD-UHFFFAOYSA-M
InChi Code
InChI=1S/C35H74NO3.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-31-38-34-35(33-36(3,4)29-30-37)39-32-28-26-24-22-20-18-16-14-12-10-8-6-2;/h35,37H,5-34H2,1-4H3;1H/q+1;/p-1
SMILES Code
OCC[N+](C)(CC(COCCCCCCCCCCCCCC)OCCCCCCCCCCCCCC)C.[Br-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 636.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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