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MedKoo Cat#: 577127 | Name: Mepamil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mepamil is a calcium channel blocker.

Chemical Structure

Mepamil
Mepamil
CAS#117721-47-8

Theoretical Analysis

MedKoo Cat#: 577127

Name: Mepamil

CAS#: 117721-47-8

Chemical Formula: C26H36N2O2

Exact Mass: 408.2777

Molecular Weight: 408.59

Elemental Analysis: C, 76.43; H, 8.88; N, 6.86; O, 7.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Mepamil
IUPAC/Chemical Name
Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-2-methyl-alpha-(1-methylethyl)-
InChi Key
WSTHECAEFYKCPL-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H36N2O2/c1-20(2)26(19-27,23-11-8-7-10-21(23)3)15-9-16-28(4)17-14-22-12-13-24(29-5)25(18-22)30-6/h7-8,10-13,18,20H,9,14-17H2,1-6H3
SMILES Code
COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccccc2C)cc1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 408.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Gersl V, Pokorná P, Rasínová S, Strídová E, Stĕpánková J, Vránová M. The effects of calcium channel blockers on the cardiovascular system of rabbits in vivo. Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1990;33(2):199-212. PMID: 2098907. 2. Ondriasová E, Ondrias K, Stasko A, Nosál R, Csöllei J. Comparison of the potency of five potential beta-adrenoceptor blocking drugs and eight calcium channel blockers to inhibit platelet aggregation and to perturb liposomal membranes prepared from platelet lipids. Physiol Res. 1992;41(4):267-72. PMID: 1363058. 3. Ondrias K, Ondriasová E, Stasko A. Perturbation effect of eight calcium channel blockers on liposomal membranes prepared from rat brain total lipids. Chem Phys Lipids. 1992 Jul;62(1):11-7. doi: 10.1016/0009-3084(92)90049-u. PMID: 1330338. 4. Stehlík P, Houbová H. Determination of mepamil in human plasma by reversed-phase high-performance liquid chromatography with fluorescence detection. J Chromatogr. 1990 Jul 13;529(1):251-7. doi: 10.1016/s0378-4347(00)83830-x. PMID: 2211940.