NPC-18915 | CAS# 179487-75-3 | inhibitor of neutophil activation

MedKoo Cat#: 414512 | Name: NPC-18915

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NPC-18915 is a benzofuran compound, inhibitor of neutophil activation.

Chemical Structure

NPC-18915

CAS#179487-75-3

Theoretical Analysis

MedKoo Cat#: 414512

Name: NPC-18915

CAS#: 179487-75-3

Chemical Formula: C23H16O3

Exact Mass: 340.1099

Molecular Weight: 340.38

Elemental Analysis: C, 81.16; H, 4.74; O, 14.10

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NPC-18915; NPC18915; NPC 18915

IUPAC/Chemical Name

Benzoic acid, 4-((1E)-2-(2-(2-benzofuranyl)phenyl)ethenyl)-

InChi Key

WLNRDTFLFIXWSX-FMIVXFBMSA-N

InChi Code

InChI=1S/C23H16O3/c24-23(25)18-13-10-16(11-14-18)9-12-17-5-1-3-7-20(17)22-15-19-6-2-4-8-21(19)26-22/h1-15H,(H,24,25)/b12-9+

SMILES Code

O=C(O)C1=CC=C(/C=C/C2=CC=CC=C2C3=CC4=CC=CC=C4O3)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 340.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wallace JL, McKnight W, Asfaha S, Liu DY. Reduction of acute and reactivated colitis in rats by an inhibitor of neutrophil activation. Am J Physiol. 1998 May;274(5):G802-8. doi: 10.1152/ajpgi.1998.274.5.G802. PMID: 9612259. 2: Yano M, Ando K, Fujino S, Liu DY, Cooper JD, Patterson GA. Delayed administration of low-dose NPC18915 ameliorates lung ischemia-reperfusion injury. J Heart Lung Transplant. 1998 Jun;17(6):622-8. PMID: 9662099.