Mecloxamine is an anticholinergic agent known for its sedative and hypnotic properties. It has been used in combination with other medications, such as caffeine, ergotamine, and acetaminophen, for the treatment of headaches and migraines. As an anticholinergic, mecloxamine likely exerts its effects by inhibiting the action of acetylcholine on muscarinic receptors, leading to reduced parasympathetic nervous system activity. This mechanism contributes to its sedative and hypnotic effects. In vitro studies have indicated that mecloxamine possesses anticholinergic activity, which may account for its sedative and hypnotic properties.
MedKoo Cat#: 577064
Name: Mecloxamine citrate
CAS#: 56050-03-4 (citrate)
Chemical Formula: C25H32ClNO8
Exact Mass: 509.1816
Molecular Weight: 509.98
Elemental Analysis: C, 58.88; H, 6.32; Cl, 6.95; N, 2.75; O, 25.10
The following data is based on the product molecular weight 509.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
