YAN7874 | CAS#unknown | Orexin agonist

MedKoo Cat#: 464866 | Name: YAN7874

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YAN7874 is a potent orexin agonist (EC50 > 3.2 uM).

Chemical Structure

YAN7874

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464866

Name: YAN7874

CAS#: unknown

Chemical Formula: C23H21Cl2N3O

Exact Mass: 425.1062

Molecular Weight: 426.34

Elemental Analysis: C, 64.80; H, 4.97; Cl, 16.63; N, 9.86; O, 3.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

YAN7874; YAN 7874; YAN-7874;

IUPAC/Chemical Name

1-(3,4-dichlorophenyl)-2-(2-imino-3-(4-methylbenzyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethan-1-ol

InChi Key

LQYDYWMFFKKSFD-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H21Cl2N3O/c1-15-6-8-16(9-7-15)13-27-20-4-2-3-5-21(20)28(23(27)26)14-22(29)17-10-11-18(24)19(25)12-17/h2-12,22,26,29H,13-14H2,1H3

SMILES Code

CC(C=C1)=CC=C1CN(C2=CC=CC=C2N3CC(O)C4=CC(Cl)=C(Cl)C=C4)C3=N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 426.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Turku A, Rinne MK, Boije Af Gennäs G, Xhaard H, Lindholm D, Kukkonen JP. Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity. PLoS One. 2017 Jun 2;12(6):e0178526. doi: 10.1371/journal.pone.0178526. PMID: 28575023; PMCID: PMC5456073.