U-26146D | CAS#11075-87-9 | antifungal antibiotic

MedKoo Cat#: 598965 | Name: U-26146D

Description:

WARNING: This product is for research use only, not for human or veterinary use.

U-26146D is a novel antifungal antibiotic.

Chemical Structure

U-26146D

CAS#11075-87-9

Theoretical Analysis

MedKoo Cat#: 598965

Name: U-26146D

CAS#: 11075-87-9

Chemical Formula: C38H74N4O14S

Exact Mass:

Molecular Weight: 843.08

Elemental Analysis: C, 54.14; H, 8.85; N, 6.65; O, 26.57; S, 3.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Lipoxamycin; U-26146D; U 26146D; U26146D;

IUPAC/Chemical Name

(S)-2-amino-N,3-dihydroxy-N-(14-methyl-3,10-dioxopentadecyl)propanamide hemisulfate

InChi Key

LQVOFMWEPHCSIY-IJBYHFJWSA-N

InChi Code

InChI=1S/2C19H36N2O5.H2O4S/c2*1-15(2)8-7-11-16(23)9-5-3-4-6-10-17(24)12-13-21(26)19(25)18(20)14-22;1-5(2,3)4/h2*15,18,22,26H,3-14,20H2,1-2H3;(H2,1,2,3,4)/t2*18-;/m00./s1

SMILES Code

OC[C@@H](C(N(CCC(CCCCCCC(CCCC(C)C)=O)=O)O)=O)N.OC[C@H](N)C(N(CCC(CCCCCCC(CCCC(C)C)=O)=O)O)=O.OS(O)(=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 843.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Mandala SM, Frommer BR, Thornton RA, Kurtz MB, Young NM, Cabello MA, Genilloud O, Liesch JM, Smith JL, Horn WS. Inhibition of serine palmitoyl-transferase activity by lipoxamycin. J Antibiot (Tokyo). 1994 Mar;47(3):376-9. PubMed PMID: 8175492. 2: Whaley HA. The structure of lipoxamycin, a novel antifungal antibiotic. J Am Chem Soc. 1971 Jul 28;93(15):3767-9. PubMed PMID: 5091204. 3: Roy SK, Inouye Y, Nakamura S, Furukawa J, Okuda S. Isolation, structural elucidation and biological properties of neoenactins B1, B2, M1 and M2, neoenactin congeners. J Antibiot (Tokyo). 1987 Mar;40(3):266-74. PubMed PMID: 3570978. 4: Whaley HA, Sebek OK, Lewis C. Production, isolation, characterization, and evaluation of lipoxamycin, a new antifungal agent. Antimicrob Agents Chemother (Bethesda). 1970;10:455-61. PubMed PMID: 5521367.