MedKoo Cat#: 464861 | Name: YCH-337

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YCH-337 is a dual tubulin−topo II inhibitor.

Chemical Structure

YCH-337
YCH-337
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464861

Name: YCH-337

CAS#: unknown

Chemical Formula: C19H14N2O3

Exact Mass: 318.1004

Molecular Weight: 318.33

Elemental Analysis: C, 71.69; H, 4.43; N, 8.80; O, 15.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
YCH-337; YCH337; YCH 337;
IUPAC/Chemical Name
(2-hydroxy-5-methoxyphenyl)(9H-pyrido[2,3-b]indol-3-yl)methanone
InChi Key
VXJGEBHBMOMZDB-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H14N2O3/c1-24-12-6-7-17(22)15(9-12)18(23)11-8-14-13-4-2-3-5-16(13)21-19(14)20-10-11/h2-10,22H,1H3,(H,20,21)
SMILES Code
O=C(C1=CC(OC)=CC=C1O)C2=CC3=C(N=C2)NC4=CC=CC=C43
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 318.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yi JM, Zhang XF, Huan XJ, Song SS, Wang W, Tian QT, Sun YM, Chen Y, Ding J, Wang YQ, Yang CH, Miao ZH. Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition. Oncotarget. 2015 Apr 20;6(11):8960-73. doi: 10.18632/oncotarget.3264. PMID: 25840421; PMCID: PMC4496195.