MedKoo Cat#: 414409 | Name: Nithiazide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nithiazide was used in veterinary medicine as an antiprotozoal agent.

Chemical Structure

Nithiazide
CAS# 139-94-6

Theoretical Analysis

MedKoo Cat#: 414409

Name: Nithiazide

CAS#: 139-94-6

Chemical Formula: C6H8N4O3S

Exact Mass: 216.0317

Molecular Weight: 216.22

Elemental Analysis: C, 33.33; H, 3.73; N, 25.91; O, 22.20; S, 14.83

Price and Availability

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1g USD 480.00 2 Weeks
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Related CAS #
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Synonym
Nithiazide; CCRIS435; CCRIS-435; CCRIS 435; HSDB7098; HSDB-7098; HSDB 7098
IUPAC/Chemical Name
1-ethyl-3-(5-nitrothiazol-2-yl)urea
InChi Key
FQSUTLQHSDLLAN-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H8N4O3S/c1-2-7-5(11)9-6-8-3-4(14-6)10(12)13/h3H,2H2,1H3,(H2,7,8,9,11)
SMILES Code
CCNC(Nc1sc([N+]([O-])=O)cn1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Nithiazide was used in veterinary medicine as an antiprotozoal agent.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 216.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: CUCKLER AC, MALANGA CM. Nithiazide. II. Effect on enterohepatitis in Turkeys. Proc Soc Exp Biol Med. 1956 Jul;92(3):485-8. doi: 10.3181/00379727-92-22520. PMID: 13359442. 2: Nithiazide. IARC Monogr Eval Carcinog Risk Chem Hum. 1983 Jul;31:179-83. PMID: 6579006. 3: National Toxicology Program. Bioassay of nithiazide for possible carcinogenicity. Natl Cancer Inst Carcinog Tech Rep Ser. 1979;146:1-107. PMID: 12799716. 4: BASSO AJ, CUCKLER AC, MALANGA CM, O'NEILL RC, PFISTER K 3rd. Nithiazide. I. Chemical and biological studies on 1-ethyl-3-(5-nitro-2-thiazolyl) urea and related compounds. Proc Soc Exp Biol Med. 1956 Jul;92(3):483-5. doi: 10.3181/00379727-92-22519. PMID: 13359441. 5: Gombar VK, Enslein K, Blake BW. Carcinogenicity of azathioprine: an S-AR investigation. Mutat Res. 1993 May;302(1):7-12. doi: 10.1016/0165-7992(93)90083-8. Erratum in: Mutat Res 1993 Aug;302(4):221. Einstein K [corrected to Enslein K]. PMID: 7683109.