KF-41399 | CAS# 291312-23-7 | chemotherapy-induced thrombocytopenia

MedKoo Cat#: 4142398 | Name: KF-41399

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KF-41399 is a novel carbazole derivative which has potential for therapy of chemotherapy-induced thrombocytopenia in patients with cancer

Chemical Structure

KF-41399

CAS#291312-23-7

Theoretical Analysis

MedKoo Cat#: 4142398

Name: KF-41399

CAS#: 291312-23-7

Chemical Formula: C27H26BrN3O3

Exact Mass: 519.1158

Molecular Weight: 520.43

Elemental Analysis: C, 62.31; H, 5.04; Br, 15.35; N, 8.07; O, 9.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KF-41399; KF41399; KF 41399

IUPAC/Chemical Name

Pyrrolo(3,4-C)carbazole-1,3(2H,6H)-dione, 4-(2-bromo-6-(2-(dimethylamino)-1-methylethoxy)phenyl)-2,6-dimethyl-

InChi Key

OWYMBHYMRQFNJU-UHFFFAOYSA-N

InChi Code

InChI=1S/C27H26BrN3O3/c1-15(14-29(2)3)34-21-12-8-10-18(28)22(21)17-13-20-23(16-9-6-7-11-19(16)30(20)4)25-24(17)26(32)31(5)27(25)33/h6-13,15H,14H2,1-5H3

SMILES Code

O=C1N(C)C(C2=C1C3=C(C=C2C4=C(OC(C)CN(C)C)C=CC=C4Br)N(C)C5=C3C=CC=C5)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 520.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Shiotsu Y, Yamashita K, Kanai F, Ikuina Y, Murakata C, Teramura M, Mizoguchi H, Tamaoki T, Akinaga S. Chemoprotective effects of KF41399, a derivative of carbazole compounds, on nimustine-induced thrombocytopenia. Blood. 2000 Jun 15;95(12):3771-80. PMID: 10845909.