MedKoo Cat#: 576897 | Name: Diflorasone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diflorasone is a corticosteroid and an anti-inflammatory agent.

Chemical Structure

Diflorasone
CAS#2557-49-5

Theoretical Analysis

MedKoo Cat#: 576897

Name: Diflorasone

CAS#: 2557-49-5

Chemical Formula: C22H28F2O5

Exact Mass: 410.1905

Molecular Weight: 410.46

Elemental Analysis: C, 64.38; H, 6.88; F, 9.26; O, 19.49

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 Weeks
200mg USD 550.00 2 Weeks
500mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Diflorasone; Florone; Maxiflor; Diflorasonum; Diflorasona; U 34865; U34865; U-34865;
IUPAC/Chemical Name
6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
InChi Key
WXURHACBFYSXBI-XHIJKXOTSA-N
InChi Code
InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1
SMILES Code
C[C@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 410.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Bluefarb SM, Howard FM, Leibsohn E, Schlagel CA, Wexler L. Diflorasone diacetate: vasoconstrictor activity and clinical efficacy of a new topical corticosteroid. J Int Med Res. 1976;4(6):454-61. doi: 10.1177/030006057600400613. PMID: 800385. 2. Johansson EA, Stiger TR. Comparative efficacy of once a day diflorasone diacetate and twice a day betamethasone valerate ointment applications in eczematous dermatitis. Curr Med Res Opin. 1984;9(4):259-64. doi: 10.1185/03007998409109589. PMID: 6510015.