Manifaxine hydrochloride | CAS# 135306-42-2 | Biochemical

MedKoo Cat#: 576863 | Name: Manifaxine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Manifaxine hydrochloride is a norepinephrine-dopamine reuptake inhibitor potentially for the treatment of attention deficit disorder.

Chemical Structure

Manifaxine hydrochloride

CAS#135306-42-2

Theoretical Analysis

MedKoo Cat#: 576863

Name: Manifaxine hydrochloride

CAS#: 135306-42-2

Chemical Formula: C12H16ClF2NO2

Exact Mass: 279.0838

Molecular Weight: 279.71

Elemental Analysis: C, 51.53; H, 5.77; Cl, 12.67; F, 13.58; N, 5.01; O, 11.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BW-1555U88; BW 1555U88; BW1555U88; Manifaxine hydrochloride; Manifaxine HCl

IUPAC/Chemical Name

2-Morpholinol, 2-(3,5-difluorophenyl)-3,5-dimethyl-, hydrochloride, (2S-(2alpha,3alpha,5alpha))-

InChi Key

OZGPVYJHWWPEFT-RGNHYFCHSA-N

InChi Code

InChI=1S/C12H15F2NO2/c1-7-6-17-12(16,8(2)15-7)9-3-10(13)5-11(14)4-9/h3-5,7-8,15-16H,6H2,1-2H3/t7-,8+,12-/m1/s1

SMILES Code

C[C@@H]1CO[C@](O)([C@H](C)N1)c2cc(F)cc(F)c2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 279.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Spraggs CF, Pillai SG, Dow D, Douglas C, McCarthy L, Manasco PK, Stubbins M, Roses AD. Pharmacogenetics and obesity: common gene variants influence weight loss response of the norepinephrine/dopamine transporter inhibitor GW320659 in obese subjects. Pharmacogenet Genomics. 2005 Dec;15(12):883-9. PubMed PMID: 16272960. 2: DeVeaugh-Geiss J, Conners CK, Sarkis EH, Winner PK, Ginsberg LD, Hemphill JM, Laurenza A, Barrows CE, Webster CJ, Stotka CJ, Asgharnejad M. GW320659 for the treatment of attention-deficit/hyperactivity disorder in children. J Am Acad Child Adolesc Psychiatry. 2002 Aug;41(8):914-20. PubMed PMID: 12162627.