MedKoo Cat#: 462449 | Name: Homodestcardin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Homodestcardin is a cyclic depsipeptide fungal metabolite that has been found in T. roseum and has immunosuppressant activity. It inhibits concanavalin A-induced proliferation of isolated mouse T cells.

Chemical Structure

Homodestcardin
Homodestcardin
CAS#917382-84-4

Theoretical Analysis

MedKoo Cat#: 462449

Name: Homodestcardin

CAS#: 917382-84-4

Chemical Formula: C32H55N5O7

Exact Mass: 621.4101

Molecular Weight: 621.82

Elemental Analysis: C, 61.81; H, 8.92; N, 11.26; O, 18.01

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Related CAS #
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Synonym
Homodestcardin
IUPAC/Chemical Name
(3S,6S,9S,16R,21S,21aS)-3,6-di((S)-sec-butyl)-16-isobutyl-5,8,9,21-tetramethyldodecahydropyrrolo[1,2-d][1]oxa[4,7,10,13,16]pentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexaone
InChi Key
AIPPDKJKKDOWTJ-MKUQIKACSA-N
InChi Code
InChI=1S/C32H55N5O7/c1-11-19(5)25-31(42)36(10)27(20(6)12-2)32(43)35(9)22(8)28(39)33-15-13-24(38)44-23(17-18(3)4)30(41)37-16-14-21(7)26(37)29(40)34-25/h18-23,25-27H,11-17H2,1-10H3,(H,33,39)(H,34,40)/t19-,20-,21-,22-,23+,25-,26-,27-/m0/s1
SMILES Code
O=C([C@@H](CC(C)C)OC1=O)N2[C@]([C@@H](C)CC2)([H])C(N[C@]([C@@H](C)CC)([H])C(N(C)[C@@](C(N([C@H](C(NCC1)=O)C)C)=O)([H])[C@@H](C)CC)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 621.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang, A.H., Wang, X.Q., Han, W.B., et al. Discovery of a new class of immunosuppressants from Trichothecium roseum co-inspired by cross-kingdom similarity in innate immunity and pharmacophore motif. Chem. Asian J. 8(12), 3101-3107 (2013).