Obovatal | CAS#83864-77-1 | Biphenyl ether lignan

MedKoo Cat#: 111032 | Name: Obovatal

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Obovatal is a biphenyl ether lignan from the leaves of Magnolia obovata Thunb

Chemical Structure

Obovatal

CAS#83864-77-1

Theoretical Analysis

MedKoo Cat#: 111032

Name: Obovatal

CAS#: 83864-77-1

Chemical Formula: C18H16O4

Exact Mass: 296.1049

Molecular Weight: 296.32

Elemental Analysis: C, 72.96; H, 5.44; O, 21.60

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

3,4-Dihydroxy-5-(4-allylphenoxy)cinnamic aldehyde; Obovatal

IUPAC/Chemical Name

(E)-3-(3-(4-allylphenoxy)-4,5-dihydroxyphenyl)acrylaldehyde

InChi Key

KGHJODCHEIEYBP-HWKANZROSA-N

InChi Code

InChI=1S/C18H16O4/c1-2-4-13-6-8-15(9-7-13)22-17-12-14(5-3-10-19)11-16(20)18(17)21/h2-3,5-12,20-21H,1,4H2/b5-3+

SMILES Code

Oc1cc(\C=C\C=O)cc(Oc2ccc(CC=C)cc2)c1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 296.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Ito K, Iida T, Ichino K, Tsunezuka M, Hattori M, Namba T. Obovatol and obovatal, novel biphenyl ether lignans from the leaves of Magnolia obovata Thunb. Chem Pharm Bull (Tokyo). 1982 Sep;30(9):3347-53. doi: 10.1248/cpb.30.3347. PMID: 7172337. 2. Lee SK, Chun HK, Yang JY, Han DC, Son KH, Kwon BM. Inhibitory effect of obovatal on the migration and invasion of HT1080 cells via the inhibition of MMP-2. Bioorg Med Chem. 2007 Jun 15;15(12):4085-90. doi: 10.1016/j.bmc.2007.03.081. Epub 2007 Mar 30. PMID: 17428670. 3. Choi DY, Lee YJ, Lee SY, Lee YM, Lee HH, Choi IS, Oh KW, Han SB, Nam SY, Hong JT. Attenuation of scopolamine-induced cognitive dysfunction by obovatol. Arch Pharm Res. 2012 Jul;35(7):1279-86. doi: 10.1007/s12272-012-0719-1. Epub 2012 Aug 3. PMID: 22864751. 4. Joo J, Lee D, Wu Z, Shin JH, Lee HS, Kwon BM, Huh TL, Kim YW, Lee SJ, Kim TW, Lee T, Liu KH. In vitro metabolism of obovatol and its effect on cytochrome P450 enzyme activities in human liver microsomes. Biopharm Drug Dispos. 2013 May;34(4):195-202. doi: 10.1002/bdd.1837. Epub 2013 Mar 26. PMID: 23446989. 5. Seo KH, Lee DY, Lee DS, Park JH, Jeong RH, Jung YJ, Shrestha S, Chung IS, Kim GS, Kim YC, Baek NI. Neolignans from the fruits of Magnolia obovata and their inhibition effect on NO production in LPS-induced RAW 264.7 cells. Planta Med. 2013 Sep;79(14):1335-40. doi: 10.1055/s-0033-1350673. Epub 2013 Aug 22. PMID: 23970426.