MedKoo Cat#: 124612 | Name: AKT-IN-18
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AKT-IN-18, an inhibitor of Akt, inhibits Akt.

Chemical Structure

AKT-IN-18
AKT-IN-18
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124612

Name: AKT-IN-18

CAS#: N/A

Chemical Formula: C19H14ClN5O2S

Exact Mass: 411.0557

Molecular Weight: 411.86

Elemental Analysis: C, 55.41; H, 3.43; Cl, 8.61; N, 17.00; O, 7.77; S, 7.78

Price and Availability

Size Price Availability Quantity
100mg USD 1,350.00 2 Weeks
200mg USD 2,050.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 6,950.00 2 Weeks
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Related CAS #
No Data
Synonym
AKT-IN-18; AKT-IN18; AKT IN-18
IUPAC/Chemical Name
(E)-N'-(4-(1H-imidazol-1-yl)benzylidene)-2-((5-chlorobenzo[d]oxazol-2-yl)thio)acetohydrazide
InChi Key
DICRBWNYEJXEKH-LSHDLFTRSA-N
InChi Code
InChI=1S/C19H14ClN5O2S/c20-14-3-6-17-16(9-14)23-19(27-17)28-11-18(26)24-22-10-13-1-4-15(5-2-13)25-8-7-21-12-25/h1-10,12H,11H2,(H,24,26)/b22-10+
SMILES Code
O=C(N/N=C/C1=CC=C(N2C=CN=C2)C=C1)CSC3=NC4=CC(Cl)=CC=C4O3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 411.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Erdönmez B, Altıntop MD, Akalın Çiftçi G, Özdemir A, Ece A. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8(22):20056-20065. doi: 10.1021/acsomega.3c02331. PMID: 37305321; PMCID: PMC10249096.