SAMS peptide | specific substrate for AMPK | CAS#125911-68-4

MedKoo Cat#: 128243 | Name: SAMS Peptide

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).

Chemical Structure

SAMS Peptide

CAS#125911-68-4

Theoretical Analysis

MedKoo Cat#: 128243

Name: SAMS Peptide

CAS#: 125911-68-4

Chemical Formula: C74H131N29O18S2

Exact Mass: 1777.9668

Molecular Weight: 1779.17

Elemental Analysis: C, 49.96; H, 7.42; N, 22.83; O, 16.19; S, 3.60

Price and Availability

Size	Price	Availability	Quantity
1mg	USD 450.00	2 Weeks

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Related CAS #

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Synonym

SAMS Peptide; SAMSPeptide; SAMS Peptide trifluoroacetate salt

IUPAC/Chemical Name

(5S,8S,11S,14S,17S,20S,26S,29S,32S,35S,38S,41S,44S)-29-((1H-imidazol-5-yl)methyl)-5-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)-38-(4-aminobutyl)-8,41,44-tris(3-((diaminomethylene)amino)propyl)-11,20-bis(hydroxymethyl)-26,32-diisobutyl-35-isopropyl-14-methyl-17-(2-(methylthio)ethyl)-6,9,12,15,18,21,24,27,30,33,36,39,42-tridecaoxo-2-thia-7,10,13,16,19,22,25,28,31,34,37,40,43-tridecaazapentatetracontan-45-oic acid

InChi Key

YJAHUEAICBOBTC-CSVPVIMBSA-N

InChi Code

InChI=1S/C74H131N29O18S2/c1-38(2)27-51(66(115)100-53(30-43-32-84-37-90-43)67(116)99-52(28-39(3)4)68(117)103-57(40(5)6)70(119)97-45(15-10-11-21-75)61(110)95-46(16-12-22-85-72(77)78)62(111)98-50(71(120)121)18-14-24-87-74(81)82)92-56(106)33-88-60(109)54(34-104)101-65(114)48(19-25-122-8)93-58(107)41(7)91-69(118)55(35-105)102-63(112)47(17-13-23-86-73(79)80)96-64(113)49(20-26-123-9)94-59(108)44(76)29-42-31-83-36-89-42/h31-32,36-41,44-55,57,104-105H,10-30,33-35,75-76H2,1-9H3,(H,83,89)(H,84,90)(H,88,109)(H,91,118)(H,92,106)(H,93,107)(H,94,108)(H,95,110)(H,96,113)(H,97,119)(H,98,111)(H,99,116)(H,100,115)(H,101,114)(H,102,112)(H,103,117)(H,120,121)(H4,77,78,85)(H4,79,80,86)(H4,81,82,87)/t41-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,57-/m0/s1

SMILES Code

C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC2=CN=CN2)N

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,779.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Davies SP, Carling D, Hardie DG. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur J Biochem. 1989 Dec 8;186(1-2):123-8. doi: 10.1111/j.1432-1033.1989.tb15185.x. PMID: 2574667.