MedKoo Cat#: 111027 | Name: Oblongine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Obolgine is a benzylisoquinoline and is extracted from the Stephania tetrandra plant. Obolgine may have potential haemodynamic effects, as it can cause a dose-dependent reduction of systolic and diastolic blood pressure.

Chemical Structure

Oblongine
Oblongine
CAS#60008-01-7

Theoretical Analysis

MedKoo Cat#: 111027

Name: Oblongine

CAS#: 60008-01-7

Chemical Formula: C19H24NO3+

Exact Mass: 314.1751

Molecular Weight: 314.40

Elemental Analysis: C, 72.58; H, 7.69; N, 4.46; O, 15.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Oblongine chloride; Oblongine
IUPAC/Chemical Name
(S)-8-hydroxy-1-(4-hydroxybenzyl)-7-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium
InChi Key
POJZOQWVMMYVBU-INIZCTEOSA-O
InChi Code
InChI=1S/C19H23NO3/c1-20(2)11-10-14-6-9-17(23-3)19(22)18(14)16(20)12-13-4-7-15(21)8-5-13/h4-9,16H,10-12H2,1-3H3,(H-,21,22)/p+1/t16-/m0/s1
SMILES Code
COc1ccc2CC[N+](C)(C)[C@@H](Cc3ccc(O)cc3)c2c1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 314.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Abdalla S, Zarga MA, Sabri S. Effects of oblongine chloride, an alkaloid from Leontice leontopetalum on guinea-pig isolated smooth muscle and heart. Gen Pharmacol. 1993 Mar;24(2):299-304. doi: 10.1016/0306-3623(93)90306-i. PMID: 8482513. 2. Tanahashi T, Su U, Nagakura N, Nayeshiro H. Quaternary isoquinoline alkaloids from Stephania cepharantha. Chem Pharm Bull (Tokyo). 2000 Mar;48(3):370-3. doi: 10.1248/cpb.48.370. PMID: 10726860. 3. Tringali C, Spatafora C, Calì V, Simmonds MS. Antifeedant constituents from Fagara macrophylla. Fitoterapia. 2001 Jun;72(5):538-43. doi: 10.1016/s0367-326x(01)00265-9. PMID: 11429249. 4. Tringali C, Spatafora C, Calì V, Simmonds MS. Antifeedant constituents from Fagara macrophylla. Fitoterapia. 2001 Jun;72(5):538-43. doi: 10.1016/s0367-326x(01)00265-9. PMID: 11429249. 5. Rukachaisirikul T, Kumjun S, Suebsakwong P, Apiratikul N, Suksamrarn A. A new pyrrole alkaloid from the roots of Cissampelos pareira. Nat Prod Res. 2021 Jan;35(1):80-87. doi: 10.1080/14786419.2019.1614576. Epub 2019 May 28. PMID: 31135214.