MedKoo Cat#: 596110 | Name: Janus green

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Janus green is a basic dye.

Chemical Structure

Janus green
Janus green
CAS#4618-88-6

Theoretical Analysis

MedKoo Cat#: 596110

Name: Janus green

CAS#: 4618-88-6

Chemical Formula: C26H23ClN6

Exact Mass: 454.1673

Molecular Weight: 454.96

Elemental Analysis: C, 68.64; H, 5.10; Cl, 7.79; N, 18.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Janus green; EINECS 225-029-8; Janus Green G; C.I. 11045;
IUPAC/Chemical Name
(E)-3-amino-7-((4-(dimethylamino)phenyl)diazenyl)-5-phenylphenazin-5-ium chloride
InChi Key
VZCCTDLWCKUBGD-BXGDTPBJSA-N
InChi Code
InChI=1S/C26H22N6.ClH/c1-31(2)21-12-9-19(10-13-21)29-30-20-11-15-24-26(17-20)32(22-6-4-3-5-7-22)25-16-18(27)8-14-23(25)28-24;/h3-17,27H,1-2H3;1H/b30-29+;
SMILES Code
CN(C1=CC=C(/N=N/C2=CC3=[N+](C4=CC=CC=C4)C5=C(C=CC(N)=C5)N=C3C=C2)C=C1)C.[Cl-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 454.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen X, Cui J, Zhai X, Zhang J, Gu Z, Zhi X, Weng W, Pan P, Cao L, Ji F, Wang Z, Su J. Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. Cell Physiol Biochem. 2018 May 10;47(1):176-190. doi: 10.1159/000489764. [Epub ahead of print] PubMed PMID: 29763919. 2: Yang J, Li Y, Xue F, Liu W, Zhang S. Exosomes derived from cardiac telocytes exert positive effects on endothelial cells. Am J Transl Res. 2017 Dec 15;9(12):5375-5387. eCollection 2017. PubMed PMID: 29312490; PubMed Central PMCID: PMC5752888. 3: Marro JB, Okoro CA, Obeng YS, Richardson KC. The Impact of Organic Additives on Copper Trench Microstructure. J Electrochem Soc. 2017;164(9):D543-D550. doi: 10.1149/2.1131707jes. Epub 2017 Jun 28. PubMed PMID: 29225367; PubMed Central PMCID: PMC5715813. 4: Yang S, Thacker Z, Allison E, Bennett M, Cole N, Pinhero PJ. Electrodeposition of Copper for Three-Dimensional Metamaterial Fabrication. ACS Appl Mater Interfaces. 2017 Nov 22;9(46):40921-40929. doi: 10.1021/acsami.7b04721. Epub 2017 Nov 8. PubMed PMID: 29064661. 5: Deng Y, Tang Q, Zhang Y, Zhang R, Wei Z, Tang X, Zhang M. Protective effect of Momordica charantia water extract against liver injury in restraint-stressed mice and the underlying mechanism. Food Nutr Res. 2017 Jul 13;61(1):1348864. doi: 10.1080/16546628.2017.1348864. eCollection 2017. PubMed PMID: 28747868; PubMed Central PMCID: PMC5510204. 6: Khafri HZ, Ghaedi M, Asfaram A, Safarpoor M. Synthesis and characterization of ZnS:Ni-NPs loaded on AC derived from apple tree wood and their applicability for the ultrasound assisted comparative adsorption of cationic dyes based on the experimental design. Ultrason Sonochem. 2017 Sep;38:371-380. doi: 10.1016/j.ultsonch.2017.03.033. Epub 2017 Mar 18. PubMed PMID: 28633837. 7: Ma HF, Liu QY, Wang YL, Yin SG. A Water-Stable Anionic Metal-Organic Framework Constructed from Columnar Zinc-Adeninate Units for Highly Selective Light Hydrocarbon Separation and Efficient Separation of Organic Dyes. Inorg Chem. 2017 Mar 6;56(5):2919-2925. doi: 10.1021/acs.inorgchem.6b03026. Epub 2017 Feb 20. PubMed PMID: 28218528. 8: Chamkouri N, Niazi A, Zare-Shahabadi V. Development of a novel pH sensor based upon Janus Green B immobilized on triacetyl cellulose membrane: Experimental design and optimization. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Mar 5;156:105-11. doi: 10.1016/j.saa.2015.11.016. Epub 2015 Dec 1. PubMed PMID: 26655070. 9: Velasquez-Vottelerd P, Anton Y, Salazar-Lugo R. Cadmium affects the mitochondrial viability and the acid soluble thiols concentration in liver, kidney, heart and gills of Ancistrus brevifilis (Eigenmann, 1920). Open Vet J. 2015;5(2):166-72. Epub 2015 Nov 20. PubMed PMID: 26623384; PubMed Central PMCID: PMC4663803. 10: Ghaedi M, Khafri HZ, Asfaram A, Goudarzi A. Response surface methodology approach for optimization of adsorption of Janus Green B from aqueous solution onto ZnO/Zn(OH)2-NP-AC: Kinetic and isotherm study. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Jan 5;152:233-40. doi: 10.1016/j.saa.2015.06.128. Epub 2015 Jul 7. PubMed PMID: 26218918. 11: Reuss B, Schroten H, Ishikawa H, Asif AR. Cross-reactivity of Antibodies Directed to the Gram-Negative Bacterium Neisseria gonorrhoeae With Heat Shock Protein 60 and ATP-Binding Protein Correlates to Reduced Mitochondrial Activity in HIBCPP Choroid Plexus Papilloma Cells. J Mol Neurosci. 2015 Sep;57(1):123-38. doi: 10.1007/s12031-015-0585-7. Epub 2015 Jun 17. PubMed PMID: 26080747. 12: Chesnokov V, Gong B, Sun C, Itakura K. Anti-cancer activity of glucosamine through inhibition of N-linked glycosylation. Cancer Cell Int. 2014 May 28;14:45. doi: 10.1186/1475-2867-14-45. eCollection 2014. PubMed PMID: 24932134; PubMed Central PMCID: PMC4057579. 13: Khan AY, Saha B, Kumar GS. Interaction of phenazinium dyes with double-stranded poly(A): spectroscopy and isothermal titration calorimetry studies. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Oct 15;131:615-24. doi: 10.1016/j.saa.2014.04.087. Epub 2014 Apr 30. PubMed PMID: 24861262. 14: Rawat S, Bruce ED. Designing quantitative structure activity relationships to predict specific toxic endpoints for polybrominated diphenyl ethers in mammalian cells. SAR QSAR Environ Res. 2014;25(7):527-49. doi: 10.1080/1062936X.2014.899512. Epub 2014 Apr 16. PubMed PMID: 24738916. 15: Wang Y, Thang N, Li Z, Zhang Y, Li J, Xue J, Gu L, Hong V, Mira L, Sung C. A staining method for assessing the viability of Esteya vermicola conidia. Curr Microbiol. 2014 Jul;69(1):53-5. doi: 10.1007/s00284-014-0553-4. Epub 2014 Mar 1. PubMed PMID: 24585076. 16: Madrakian T, Afkhami A, Ahmadi M. Adsorption and kinetic studies of seven different organic dyes onto magnetite nanoparticles loaded tea waste and removal of them from wastewater samples. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Dec;99:102-9. doi: 10.1016/j.saa.2012.09.025. Epub 2012 Sep 16. PubMed PMID: 23058993. 17: Smith VA, Johnson TK. Identification and evaluation of a thinning agent compatible with MegaCell DCS, an animal product-free corneal storage medium. Graefes Arch Clin Exp Ophthalmol. 2012 Dec;250(12):1777-86. doi: 10.1007/s00417-012-2126-1. Epub 2012 Aug 12. PubMed PMID: 23011001; PubMed Central PMCID: PMC3501186. 18: Madrakian T, Afkhami A, Ahmadi M, Bagheri H. Removal of some cationic dyes from aqueous solutions using magnetic-modified multi-walled carbon nanotubes. J Hazard Mater. 2011 Nov 30;196:109-14. doi: 10.1016/j.jhazmat.2011.08.078. Epub 2011 Sep 6. Erratum in: J Hazard Mater. 2012 Jun 15;219-220:289. PubMed PMID: 21930344. 19: Zheng Y, Li H, Manole CG, Sun A, Ge J, Wang X. Telocytes in trachea and lungs. J Cell Mol Med. 2011 Oct;15(10):2262-8. doi: 10.1111/j.1582-4934.2011.01404.x. PubMed PMID: 21810171; PubMed Central PMCID: PMC4394233. 20: Johansson HE, Johansson MK, Wong AC, Armstrong ES, Peterson EJ, Grant RE, Roy MA, Reddington MV, Cook RM. BTI1, an azoreductase with pH-dependent substrate specificity. Appl Environ Microbiol. 2011 Jun;77(12):4223-5. doi: 10.1128/AEM.02289-10. Epub 2011 Apr 29. PubMed PMID: 21531830; PubMed Central PMCID: PMC3131635.