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MedKoo Cat#: 414128 | Name: Etiproston

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Etiproston is a synthetic prostaglandin PGF(2alpha) analog.

Chemical Structure

Etiproston
Etiproston
CAS#59619-81-7

Theoretical Analysis

MedKoo Cat#: 414128

Name: Etiproston

CAS#: 59619-81-7

Chemical Formula: C24H32O7

Exact Mass: 432.2148

Molecular Weight: 432.51

Elemental Analysis: C, 66.65; H, 7.46; O, 25.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Etiproston; BRN1274276; BRN-1274276; BRN 1274276
IUPAC/Chemical Name
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-2-(2-(phenoxymethyl)-1,3-dioxolan-2-yl)vinyl)cyclopentyl)-5-heptenoic acid
InChi Key
BPALXSWPHQNCAA-RLJNYRALSA-N
InChi Code
InChI=1S/C24H32O7/c25-21-16-22(26)20(19(21)10-6-1-2-7-11-23(27)28)12-13-24(30-14-15-31-24)17-29-18-8-4-3-5-9-18/h1,3-6,8-9,12-13,19-22,25-26H,2,7,10-11,14-17H2,(H,27,28)/b6-1-,13-12+/t19-,20-,21+,22-/m1/s1
SMILES Code
O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/C2(COC3=CC=CC=C3)OCCO2)[C@H](O)C[C@@H]1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 432.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Benech H, Brune P, Pruvost A, Archimbault P, Guillot P, Murphys RC, Maclouf J, Grognet JM. Fate of etiproston, a synthetic analogue of PGF2 alpha, in cows. J Vet Pharmacol Ther. 1994 Oct;17(5):339-44. doi: 10.1111/j.1365-2885.1994.tb00256.x. PMID: 7853457. 2: Kirihara N, Naganawa A, Hori T, Kawakami E, Tsutsui T. Influence of a PGF2alpha-analogue, etiproston tromethamine, on the functional corpus luteum of dogs. J Vet Med Sci. 2005 Jan;67(1):1-6. doi: 10.1292/jvms.67.1. PMID: 15699586. 3: van Miert AS, van Duin CT. Feed intake and rumen motility in dwarf goats. Effects of some alpha 2-adrenergic agonists, prostaglandins and posterior pituitary hormones. Vet Res Commun. 1991;15(1):57-67. doi: 10.1007/BF00497791. PMID: 1675505.